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Synthesis and Pharmacology of a Novel µ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template.
Faouzi, Abdelfattah; Uprety, Rajendra; Gomes, Ivone; Massaly, Nicolas; Keresztes, Attila I; Le Rouzic, Valerie; Gupta, Achla; Zhang, Tiffany; Yoon, Hye Jean; Ansonoff, Michael; Allaoa, Abdullah; Pan, Ying Xian; Pintar, John; Morón, Jose A; Streicher, John M; Devi, Lakshmi A; Majumdar, Susruta.
Affiliation
  • Faouzi A; Center for Clinical Pharmacology, St Louis College of Pharmacy and Washington University, School of Medicine, St. Louis, Missouri 63110, United States.
  • Uprety R; Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Gomes I; Department of Neurology and Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.
  • Massaly N; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.
  • Keresztes AI; Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Le Rouzic V; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arkansas 85724, United States.
  • Gupta A; Department of Neurology and Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.
  • Zhang T; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.
  • Yoon HJ; Department of Neurology and Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.
  • Ansonoff M; Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Allaoa A; Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, United States.
  • Pan YX; Department of Neurology and Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.
  • Pintar J; Department of Neurology and Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States.
  • Morón JA; Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, United States.
  • Streicher JM; Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Devi LA; Department of Neuroscience and Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
  • Majumdar S; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arkansas 85724, United States.
J Med Chem ; 63(22): 13618-13637, 2020 11 25.
Article in En | MEDLINE | ID: mdl-33170687
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fentanyl / Receptors, Opioid, delta Limits: Animals / Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fentanyl / Receptors, Opioid, delta Limits: Animals / Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2020 Document type: Article Affiliation country: Country of publication: