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Inhibiting glycolysis rescues memory impairment in an intellectual disability Gdi1-null mouse.
D'Adamo, Patrizia; Horvat, Anemari; Gurgone, Antonia; Mignogna, Maria Lidia; Bianchi, Veronica; Masetti, Michela; Ripamonti, Maddalena; Taverna, Stefano; Velebit, Jelena; Malnar, Maja; Muhic, Marko; Fink, Katja; Bachi, Angela; Restuccia, Umberto; Belloli, Sara; Moresco, Rosa Maria; Mercalli, Alessia; Piemonti, Lorenzo; Potokar, Maja; Bobnar, Sasa Trkov; Kreft, Marko; Chowdhury, Helena H; Stenovec, Matjaz; Vardjan, Nina; Zorec, Robert.
Affiliation
  • D'Adamo P; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy; University of Ljubljana, Faculty of Medicine, Institute of Pathophysiology, Laboratory of Neuroendocrinology - Molecular Cell Physiology, Ljubljana, Slovenia; Celica Biomedical, Laboratory for Cell Engineering, Ljubljan
  • Horvat A; University of Ljubljana, Faculty of Medicine, Institute of Pathophysiology, Laboratory of Neuroendocrinology - Molecular Cell Physiology, Ljubljana, Slovenia; Celica Biomedical, Laboratory for Cell Engineering, Ljubljana, Slovenia.
  • Gurgone A; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Mignogna ML; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Bianchi V; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Masetti M; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Ripamonti M; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Taverna S; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.
  • Velebit J; University of Ljubljana, Faculty of Medicine, Institute of Pathophysiology, Laboratory of Neuroendocrinology - Molecular Cell Physiology, Ljubljana, Slovenia; Celica Biomedical, Laboratory for Cell Engineering, Ljubljana, Slovenia.
  • Malnar M; University of Ljubljana, Faculty of Medicine, Institute of Pathophysiology, Laboratory of Neuroendocrinology - Molecular Cell Physiology, Ljubljana, Slovenia.
  • Muhic M; University of Ljubljana, Faculty of Medicine, Institute of Pathophysiology, Laboratory of Neuroendocrinology - Molecular Cell Physiology, Ljubljana, Slovenia.
  • Fink K; University of Ljubljana, Faculty of Medicine, Institute of Pathophysiology, Laboratory of Neuroendocrinology - Molecular Cell Physiology, Ljubljana, Slovenia.
  • Bachi A; IFOM, the FIRC Institute of Molecular Oncology, Milan, Italy.
  • Restuccia U; IFOM, the FIRC Institute of Molecular Oncology, Milan, Italy.
  • Belloli S; Institute of Bioimaging and Physiology, CNR, Segrate (MI), Italy; Experimental Imaging Center (EIC), San Raffaele Scientific Institute, Milan, Italy.
  • Moresco RM; Experimental Imaging Center (EIC), San Raffaele Scientific Institute, Milan, Italy; Medicine and Surgery Department, University of Milano-Bicocca, Monza (MB), Italy.
  • Mercalli A; Diabetes Research Institute, IRCCS Ospedale San Raffaele, Milano, Italy.
  • Piemonti L; Diabetes Research Institute, IRCCS Ospedale San Raffaele, Milano, Italy; Università Vita-Salute San Raffaele, Milano, Italy.
  • Potokar M; University of Ljubljana, Faculty of Medicine, Institute of Pathophysiology, Laboratory of Neuroendocrinology - Molecular Cell Physiology, Ljubljana, Slovenia; Celica Biomedical, Laboratory for Cell Engineering, Ljubljana, Slovenia.
  • Bobnar ST; University of Ljubljana, Faculty of Medicine, Institute of Pathophysiology, Laboratory of Neuroendocrinology - Molecular Cell Physiology, Ljubljana, Slovenia; Celica Biomedical, Laboratory for Cell Engineering, Ljubljana, Slovenia.
  • Kreft M; University of Ljubljana, Faculty of Medicine, Institute of Pathophysiology, Laboratory of Neuroendocrinology - Molecular Cell Physiology, Ljubljana, Slovenia; Celica Biomedical, Laboratory for Cell Engineering, Ljubljana, Slovenia; University of Ljubljana, Biotechnical Faculty, Department of Biology
  • Chowdhury HH; University of Ljubljana, Faculty of Medicine, Institute of Pathophysiology, Laboratory of Neuroendocrinology - Molecular Cell Physiology, Ljubljana, Slovenia; Celica Biomedical, Laboratory for Cell Engineering, Ljubljana, Slovenia.
  • Stenovec M; University of Ljubljana, Faculty of Medicine, Institute of Pathophysiology, Laboratory of Neuroendocrinology - Molecular Cell Physiology, Ljubljana, Slovenia; Celica Biomedical, Laboratory for Cell Engineering, Ljubljana, Slovenia.
  • Vardjan N; University of Ljubljana, Faculty of Medicine, Institute of Pathophysiology, Laboratory of Neuroendocrinology - Molecular Cell Physiology, Ljubljana, Slovenia; Celica Biomedical, Laboratory for Cell Engineering, Ljubljana, Slovenia. Electronic address: nina.vardjan@mf.uni-lj.si.
  • Zorec R; University of Ljubljana, Faculty of Medicine, Institute of Pathophysiology, Laboratory of Neuroendocrinology - Molecular Cell Physiology, Ljubljana, Slovenia; Celica Biomedical, Laboratory for Cell Engineering, Ljubljana, Slovenia. Electronic address: robert.zorec@mf.uni-lj.si.
Metabolism ; 116: 154463, 2021 03.
Article in En | MEDLINE | ID: mdl-33309713
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Guanine Nucleotide Dissociation Inhibitors / Deoxyglucose / Glycolysis / Memory Disorders / Intellectual Disability Limits: Animals Language: En Journal: Metabolism Year: 2021 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Guanine Nucleotide Dissociation Inhibitors / Deoxyglucose / Glycolysis / Memory Disorders / Intellectual Disability Limits: Animals Language: En Journal: Metabolism Year: 2021 Document type: Article Country of publication: