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Single cell analysis reveals distinct immune landscapes in transplant and primary sarcomas that determine response or resistance to immunotherapy.
Wisdom, Amy J; Mowery, Yvonne M; Hong, Cierra S; Himes, Jonathon E; Nabet, Barzin Y; Qin, Xiaodi; Zhang, Dadong; Chen, Lan; Fradin, Hélène; Patel, Rutulkumar; Bassil, Alex M; Muise, Eric S; King, Daniel A; Xu, Eric S; Carpenter, David J; Kent, Collin L; Smythe, Kimberly S; Williams, Nerissa T; Luo, Lixia; Ma, Yan; Alizadeh, Ash A; Owzar, Kouros; Diehn, Maximilian; Bradley, Todd; Kirsch, David G.
Affiliation
  • Wisdom AJ; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27708, USA.
  • Mowery YM; Department of Radiation Oncology, Duke University Medical Center, Durham, NC, 27708, USA. yvonne.mowery@duke.edu.
  • Hong CS; Duke Cancer Institute, Durham, NC, 27708, USA. yvonne.mowery@duke.edu.
  • Himes JE; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27708, USA.
  • Nabet BY; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27708, USA.
  • Qin X; Stanford Cancer Institute, Stanford University, Stanford, CA, 94305, USA.
  • Zhang D; Department of Oncology Biomarker Development, Genentech, South San Francisco, CA, 94080, USA.
  • Chen L; Duke Cancer Institute, Durham, NC, 27708, USA.
  • Fradin H; Duke Cancer Institute, Durham, NC, 27708, USA.
  • Patel R; Merck & Co., Inc, Kenilworth, NJ, 07033, USA.
  • Bassil AM; Duke Center for Genomic and Computational Biology, Durham, NC, 27708, USA.
  • Muise ES; Department of Radiation Oncology, Duke University Medical Center, Durham, NC, 27708, USA.
  • King DA; Department of Radiation Oncology, Duke University Medical Center, Durham, NC, 27708, USA.
  • Xu ES; Merck & Co., Inc, Kenilworth, NJ, 07033, USA.
  • Carpenter DJ; Stanford Cancer Institute, Stanford University, Stanford, CA, 94305, USA.
  • Kent CL; Division of Oncology, Department of Medicine, Stanford University, Stanford, CA, 94305, USA.
  • Smythe KS; Department of Radiation Oncology, Duke University Medical Center, Durham, NC, 27708, USA.
  • Williams NT; Department of Radiation Oncology, Duke University Medical Center, Durham, NC, 27708, USA.
  • Luo L; Department of Radiation Oncology, Duke University Medical Center, Durham, NC, 27708, USA.
  • Ma Y; Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
  • Alizadeh AA; Department of Radiation Oncology, Duke University Medical Center, Durham, NC, 27708, USA.
  • Owzar K; Department of Radiation Oncology, Duke University Medical Center, Durham, NC, 27708, USA.
  • Diehn M; Department of Radiation Oncology, Duke University Medical Center, Durham, NC, 27708, USA.
  • Bradley T; Stanford Cancer Institute, Stanford University, Stanford, CA, 94305, USA.
  • Kirsch DG; Division of Oncology, Department of Medicine, Stanford University, Stanford, CA, 94305, USA.
Nat Commun ; 11(1): 6410, 2020 12 17.
Article in En | MEDLINE | ID: mdl-33335088
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoma / Single-Cell Analysis / Tumor Microenvironment Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoma / Single-Cell Analysis / Tumor Microenvironment Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Document type: Article Affiliation country: Country of publication: