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Gastrointestinal Symptoms in 2- to 5-Year-Old Children in the Study to Explore Early Development.
Reynolds, Ann M; Soke, Gnakub N; Sabourin, Katherine R; Croen, Lisa A; Daniels, Julie L; Fallin, M Daniele; Kral, Tanja V E; Lee, Li- Ching; Newschaffer, Craig J; Pinto-Martin, Jennifer A; Schieve, Laura A; Sims, Amy; Wiggins, Lisa; Levy, Susan E.
Affiliation
  • Reynolds AM; University of Colorado, School of Medicine, 13123 East 16th Ave, B-140, Aurora, CO, 80045, USA. ann.reynolds@childrenscolorado.org.
  • Soke GN; National Center On Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 4770 Buford Highway, Chamblee, GA, S106-330341, USA.
  • Sabourin KR; Polio Eradication Branch at the Centers for Disease Control and Prevention, Center for Global Health, Global Immunization Division, 1600 Clifton Rd, Atlanta, NE, 30333, USA.
  • Croen LA; University of Colorado, School of Medicine, 13123 East 16th Ave, B-140, Aurora, CO, 80045, USA.
  • Daniels JL; Kaiser Permanent, 3600 Broadway, Oakland, CA, 94611, USA.
  • Fallin MD; University of North Carolina at Chapel Hill, Campus Box 7435, Chapel Hill, NC, 27599, USA.
  • Kral TVE; Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Baltimore, MD, HH85021205, USA.
  • Lee LC; University of Pennsylvania, 418 Curie Boulevard, Philadelphia, PA, 19104, USA.
  • Newschaffer CJ; Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Baltimore, MD, HH85021205, USA.
  • Pinto-Martin JA; Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Baltimore, MD, HH85021205, USA.
  • Schieve LA; The Pennsylvania State University, College of Health and Human Development, 325 Health and Human Development Building, University Park, PA, 16802, USA.
  • Sims A; University of Pennsylvania, 418 Curie Boulevard, Philadelphia, PA, 19104, USA.
  • Wiggins L; National Center On Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 4770 Buford Highway, Chamblee, GA, S106-330341, USA.
  • Levy SE; Michigan State University, 909 Wilson Road, East Lansing, MI, B50048824, USA.
J Autism Dev Disord ; 51(11): 3806-3817, 2021 Nov.
Article in En | MEDLINE | ID: mdl-33394243
ABSTRACT
Gastrointestinal symptoms (GIS) are commonly reported in children with autism spectrum disorder (ASD). This multi-site study evaluated the prevalence of GIS in preschool-aged children with ASD/(n = 672), with other developmental delays (DD)/(n = 938), and children in the general population (POP)/(n = 851). After adjusting for covariates, children in the ASD group were over 3 times more likely to have parent-reported GIS than the POP group, and almost 2 times more likely than the DD group. Children with GIS from all groups had more behavioral and sleep problems. Within the ASD group, children with developmental regression had more GIS than those without; however, there were no differences in autism severity scores between children with and without GIS. These findings have implications for clinical management.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Autism Spectrum Disorder / Gastrointestinal Diseases Type of study: Clinical_trials / Diagnostic_studies / Prevalence_studies / Risk_factors_studies Limits: Child / Child, preschool / Humans Language: En Journal: J Autism Dev Disord Year: 2021 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Autism Spectrum Disorder / Gastrointestinal Diseases Type of study: Clinical_trials / Diagnostic_studies / Prevalence_studies / Risk_factors_studies Limits: Child / Child, preschool / Humans Language: En Journal: J Autism Dev Disord Year: 2021 Document type: Article Affiliation country: