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Treatment with a triazole inhibitor of the mitochondrial permeability transition pore fully corrects the pathology of sapje zebrafish lacking dystrophin.
Stocco, Anna; Smolina, Natalia; Sabatelli, Patrizia; Sileikyte, Justina; Artusi, Edoardo; Mouly, Vincent; Cohen, Michael; Forte, Michael; Schiavone, Marco; Bernardi, Paolo.
Affiliation
  • Stocco A; Department of Biomedical Sciences and CNR Neuroscience Institute, University of Padova, Padova, Italy.
  • Smolina N; Department of Biomedical Sciences and CNR Neuroscience Institute, University of Padova, Padova, Italy.
  • Sabatelli P; CNR-Institute of Molecular Genetics "Luigi Luca Cavalli-Sforza"-Unit of Bologna, Bologna, Italy; IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
  • Sileikyte J; Vollum Institute and Department of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, OR, USA.
  • Artusi E; Department of Biomedical Sciences and CNR Neuroscience Institute, University of Padova, Padova, Italy.
  • Mouly V; Center for Research in Myology UMRS 974, Sorbonne Université, INSERM, Myology Institute, Paris, France.
  • Cohen M; Vollum Institute and Department of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, OR, USA.
  • Forte M; Vollum Institute and Department of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, OR, USA.
  • Schiavone M; Department of Biomedical Sciences and CNR Neuroscience Institute, University of Padova, Padova, Italy. Electronic address: marco.schiavone@unibs.it.
  • Bernardi P; Department of Biomedical Sciences and CNR Neuroscience Institute, University of Padova, Padova, Italy. Electronic address: bernardi@bio.unipd.it.
Pharmacol Res ; 165: 105421, 2021 03.
Article in En | MEDLINE | ID: mdl-33429034
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triazoles / Zebrafish Proteins / Mitochondrial Permeability Transition Pore / Membrane Proteins / Muscle Proteins Limits: Animals / Humans Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2021 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triazoles / Zebrafish Proteins / Mitochondrial Permeability Transition Pore / Membrane Proteins / Muscle Proteins Limits: Animals / Humans Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2021 Document type: Article Affiliation country: Country of publication: