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A novel model of chronic limb ischemia to therapeutically evaluate the angiogenic effects of drug candidates.
Shimatani, Kenichiro; Sato, Hiromu; Saito, Atsuhiro; Sasai, Masao; Watanabe, Kenichi; Mizukami, Kazuhiko; Kamohara, Masazumi; Miyagawa, Shigeru; Sawa, Yoshiki.
Affiliation
  • Shimatani K; Drug Discovery Research, Astellas Pharma Incorporated, Ibaraki, Japan.
  • Sato H; Drug Discovery Research, Astellas Pharma Incorporated, Ibaraki, Japan.
  • Saito A; Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
  • Sasai M; Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
  • Watanabe K; Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
  • Mizukami K; Drug Discovery Research, Astellas Pharma Incorporated, Ibaraki, Japan.
  • Kamohara M; Drug Discovery Research, Astellas Pharma Incorporated, Ibaraki, Japan.
  • Miyagawa S; Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
  • Sawa Y; Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Am J Physiol Heart Circ Physiol ; 320(3): H1124-H1135, 2021 03 01.
Article in En | MEDLINE | ID: mdl-33481698
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Muscle, Skeletal / Neovascularization, Physiologic / Angiogenesis Inducing Agents / Drug Evaluation, Preclinical / Cilostazol / Ischemia Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2021 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Muscle, Skeletal / Neovascularization, Physiologic / Angiogenesis Inducing Agents / Drug Evaluation, Preclinical / Cilostazol / Ischemia Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2021 Document type: Article Affiliation country: Country of publication: