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A novel podocyte protein, R3h domain containing-like, inhibits TGF-ß-induced p38 MAPK and regulates the structure of podocytes and glomerular basement membrane.
Ishikawa, Takahiro; Takemoto, Minoru; Akimoto, Yoshihiro; Takada-Watanabe, Aki; Yan, Kunimasa; Sakamoto, Kenichi; Maezawa, Yoshiro; Suguro, Miyuki; He, Liqun; Tryggvason, Karl; Betsholtz, Christer; Yokote, Koutaro.
Affiliation
  • Ishikawa T; Department of Endocrinology, Hematology, and Gerontology, Chiba University Graduate School of Medicine, Chiba, 260-8670, Japan.
  • Takemoto M; Department of Diabetes, Metabolism and Endocrinology, School of Medicine, International University of Health and Welfare, 4-3, Kozunomori, Narita, Chiba, 286-8686, Japan. minoru.takemoto@faculty.chiba-u.jp.
  • Akimoto Y; Department of Anatomy, Kyorin University School of Medicine, Mitaka, Tokyo, Japan.
  • Takada-Watanabe A; Department of Endocrinology, Hematology, and Gerontology, Chiba University Graduate School of Medicine, Chiba, 260-8670, Japan.
  • Yan K; Department of Pediatrics, Kyorin University School of Medicine, Mitaka, Tokyo, Japan.
  • Sakamoto K; Department of Endocrinology, Hematology, and Gerontology, Chiba University Graduate School of Medicine, Chiba, 260-8670, Japan.
  • Maezawa Y; Department of Endocrinology, Hematology, and Gerontology, Chiba University Graduate School of Medicine, Chiba, 260-8670, Japan.
  • Suguro M; Aichi Cancer Center Research Institute, Nagoya, Japan.
  • He L; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
  • Tryggvason K; Cardiovascular and Metabolic Disorders Program, Duke-NUS Graduate Medical School Singapore, Singapore, Singapore.
  • Betsholtz C; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
  • Yokote K; Department of Medicine Huddinge, Karolinska Institutet, Campus Flemingsberg, SE-141 57, Huddinge, Sweden.
J Mol Med (Berl) ; 99(6): 859-876, 2021 06.
Article in En | MEDLINE | ID: mdl-33620517
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers / Transforming Growth Factor beta / P38 Mitogen-Activated Protein Kinases / Glomerular Basement Membrane / Podocytes Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Mol Med (Berl) Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2021 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers / Transforming Growth Factor beta / P38 Mitogen-Activated Protein Kinases / Glomerular Basement Membrane / Podocytes Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Mol Med (Berl) Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2021 Document type: Article Affiliation country: Country of publication: