Isothiazolinones Common in Children's Toy Slime.
Dermatitis
; 32(6): 413-420, 2021.
Article
in En
| MEDLINE
| ID: mdl-33629968
ABSTRACT
BACKGROUND:
Contact dermatitis to homemade slime has been frequently reported, with isothiazolinones as a likely sensitizer. Little is known on the presence of these preservatives in commercial, store-bought slime products.OBJECTIVES:
The aims of the study were to review the literature on "slime dermatitis" and to assess for the presence of isothiazolinones in commercially available slime products and homemade slime components.METHODS:
An experimental, colorimetric spot test was used to verify the presence of isothiazolinones in 38 slime products of the 16 best-selling commercial slime kits, 1 finished homemade slime, and 4 common components of homemade slime. High-performance liquid chromatography with UV detection was performed on 8 commercial slime products.RESULTS:
According to the spot test, 27 (71%) of the 38 commercial slime products contained isothiazolinones. High-performance liquid chromatography with UV detection analyses indicated, however, that false-positives and false-negatives readily occur isothiazolinone content was correctly identified in only 4 (50%) of the 8 samples.CONCLUSIONS:
This study is the first to demonstrate the presence of isothiazolinones in commercial slime toys. Although the colorimetric spot test may have some utility as a screening assay, it is far from specific and likely not sensitive enough to reliably identify methylisothiazolinone.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Play and Playthings
/
Preservatives, Pharmaceutical
/
Thiazoles
/
Dermatitis, Allergic Contact
Limits:
Child
/
Humans
Language:
En
Journal:
Dermatitis
Journal subject:
DERMATOLOGIA
Year:
2021
Document type:
Article