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Treatment of 13-cis retinoic acid and 1,25-dihydroxyvitamin D3 inhibits TNF-alpha-mediated expression of MMP-9 protein and cell invasion through the suppression of JNK pathway and microRNA 221 in human pancreatic adenocarcinoma cancer cells.
Cheng, Yen-Huang; Chiang, En-Pei Isabel; Syu, Jia-Ning; Chao, Che-Yi; Lin, Hung-Yu; Lin, Cheng-Chieh; Yang, Mei-Due; Tsai, Shu-Yao; Tang, Feng-Yao.
Affiliation
  • Cheng YH; Department of Emergency Medicine, Show Chwan Memorial Hospital, Changhua, Taiwan.
  • Chiang EI; Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, Taiwan.
  • Syu JN; Innovation and Development Center of Sustainable Agriculture (IDCSA), National Chung Hsing University, Taichung, Taiwan.
  • Chao CY; Biomedical Science Laboratory, Department of Nutrition, China Medical University, Taichung, Taiwan.
  • Lin HY; Department of Food Nutrition and Health Biotechnology, Asia University, Taichung, Taiwan.
  • Lin CC; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan.
  • Yang MD; Research Assistant Center, Show Chwan Memorial Hospital, Changhua, Taiwan.
  • Tsai SY; School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan.
  • Tang FY; Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan.
PLoS One ; 16(3): e0247550, 2021.
Article in En | MEDLINE | ID: mdl-33730072
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Calcitriol / Isotretinoin / Adenocarcinoma / Cell Movement / Tumor Necrosis Factor-alpha / Matrix Metalloproteinase 9 / MAP Kinase Signaling System / MicroRNAs / JNK Mitogen-Activated Protein Kinases Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2021 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Calcitriol / Isotretinoin / Adenocarcinoma / Cell Movement / Tumor Necrosis Factor-alpha / Matrix Metalloproteinase 9 / MAP Kinase Signaling System / MicroRNAs / JNK Mitogen-Activated Protein Kinases Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2021 Document type: Article Affiliation country: Country of publication: