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Nanobody-Based Quantification of GTP-Bound RHO Conformation Reveals RHOA and RHOC Activation Independent from Their Total Expression in Breast Cancer.
Keller, Laura; Tardy, Claudine; Ligat, Laetitia; Gilhodes, Julia; Filleron, Thomas; Bery, Nicolas; Rochaix, Philippe; Aquilina, Alexis; Bdioui, Sara; Roux, Thomas; Trinquet, Eric; Favre, Gilles; Olichon, Aurélien.
Affiliation
  • Keller L; Centre de Recherche en Cancérologie de Toulouse (CRCT), INSERM, Université de Toulouse, CNRS, UPS, Toulouse 31037, France.
  • Tardy C; Laboratoire de Biologie Médicale Oncologique, Institut Claudius Regaud, IUCT-Oncopôle, Toulouse 31037, France.
  • Ligat L; Centre de Recherche en Cancérologie de Toulouse (CRCT), INSERM, Université de Toulouse, CNRS, UPS, Toulouse 31037, France.
  • Gilhodes J; Le Pôle Technologique du Centre de Recherches en Cancérologie de Toulouse, plateau de protéomique, Toulouse 31037, France.
  • Filleron T; Service de Biostatistiques, Institut Claudius Regaud, IUCT-Oncopôle, Toulouse 31059, France.
  • Bery N; Service de Biostatistiques, Institut Claudius Regaud, IUCT-Oncopôle, Toulouse 31059, France.
  • Rochaix P; Centre de Recherche en Cancérologie de Toulouse (CRCT), INSERM, Université de Toulouse, CNRS, UPS, Toulouse 31037, France.
  • Aquilina A; Laboratoire de Biologie Médicale Oncologique, Institut Claudius Regaud, IUCT-Oncopôle, Toulouse 31037, France.
  • Bdioui S; Cisbio Bioassays, Codolet 31059, France.
  • Roux T; Cisbio Bioassays, Codolet 31059, France.
  • Trinquet E; Cisbio Bioassays, Codolet 31059, France.
  • Favre G; Cisbio Bioassays, Codolet 31059, France.
  • Olichon A; Centre de Recherche en Cancérologie de Toulouse (CRCT), INSERM, Université de Toulouse, CNRS, UPS, Toulouse 31037, France.
Anal Chem ; 93(15): 6104-6111, 2021 04 20.
Article in En | MEDLINE | ID: mdl-33825439
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / RhoA GTP-Binding Protein / RhoC GTP-Binding Protein Limits: Female / Humans Language: En Journal: Anal Chem Year: 2021 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / RhoA GTP-Binding Protein / RhoC GTP-Binding Protein Limits: Female / Humans Language: En Journal: Anal Chem Year: 2021 Document type: Article Affiliation country: Country of publication: