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Paediatric long term continuous positive airway pressure and noninvasive ventilation in France: A cross-sectional study.
Fauroux, Brigitte; Khirani, Sonia; Amaddeo, Alessandro; Massenavette, Bruno; Bierme, Priscille; Taytard, Jessica; Stremler, Nathalie; Baravalle-Einaudi, Melisande; Mazenq, Julie; Ioan, Iulia; Schweitzer, Cyril; Lampin, Marie Emilie; Binoche, Alexandra; Mordacq, Clemence; Bergounioux, Jean; Mbieleu, Blaise; Rubinsztajn, Robert; Sigur, Elodie; Labouret, Geraldine; Genevois, Aline; Becourt, Arnaud; Hullo, Eglantine; Pin, Isabelle; Debelleix, Stéphane; Galodé, François; Bui, Stéphanie; Moreau, Johan; Renoux, Marie Catherine; Matecki, Stefan; Lavadera, Marc Lubrano; Heyman, Rachel; Pomedio, Michael; Le Clainche, Laurence; Bokov, Plamen; Masson, Alexandra; Hangard, Pauline; Menetrey, Celine; Jokic, Mikael; Gachelin, Elsa; Perisson, Caroline; Pervillé, Anne; Fina, Agnes; Giovannini-Chami, Lisa; Fleurence, Emmanuelle; Barzic, Audrey; Breining, Audrey; Ollivier, Morgane; Labbé, Guillaume; Coutier, Laurianne; Aubertin, Guillaume.
Affiliation
  • Fauroux B; Pediatric Noninvasive Ventilation and Sleep Unit, AP-HP, Hôpital Necker-Enfants Malades, F-75015, Paris, France; Université de Paris, VIFASOM, F-75004, Paris, France. Electronic address: brigitte.fauroux@aphp.fr.
  • Khirani S; Pediatric Noninvasive Ventilation and Sleep Unit, AP-HP, Hôpital Necker-Enfants Malades, F-75015, Paris, France; Université de Paris, VIFASOM, F-75004, Paris, France; ASV Santé, F-92000, Gennevilliers, France.
  • Amaddeo A; Pediatric Noninvasive Ventilation and Sleep Unit, AP-HP, Hôpital Necker-Enfants Malades, F-75015, Paris, France; Université de Paris, VIFASOM, F-75004, Paris, France.
  • Massenavette B; Paediatric Intensive Care Unit, Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant, 69677, Bron, France.
  • Bierme P; Pediatric Pulmonology and Allergology Unit, Hospices Civils de Lyon, 69677, Bron, France.
  • Taytard J; Pediatric Pulmonology Department, AP-HP, Hôpital Armand Trousseau, F-75012, Paris, France; Sorbonne Université, INSERM UMR-S, 1158, Paris, France.
  • Stremler N; Pediatric Ventilation Unit, Pediatric Department, AP-HM, Hôpital La Timone, 13385, Marseille, France.
  • Baravalle-Einaudi M; Pediatric Ventilation Unit, Pediatric Department, AP-HM, Hôpital La Timone, 13385, Marseille, France.
  • Mazenq J; Pediatric Ventilation Unit, Pediatric Department, AP-HM, Hôpital La Timone, 13385, Marseille, France.
  • Ioan I; Pediatric Department, University Children's Hospital, CHRU Nanc, Université de Lorraine, DevAH, F-54000, Nancy, France.
  • Schweitzer C; Pediatric Department, University Children's Hospital, CHRU Nanc, Université de Lorraine, DevAH, F-54000, Nancy, France.
  • Lampin ME; Pediatric Intensive Care Unit, Hôpital Jeanne de Flandre, CHU Lille, Avenue Eugène Avinée, 59037, Lille Cédex, France.
  • Binoche A; Pediatric Intensive Care Unit, Hôpital Jeanne de Flandre, CHU Lille, Avenue Eugène Avinée, 59037, Lille Cédex, France.
  • Mordacq C; Pediatic Pulmonology and Allergology Unit, Hôpital Jeanne de Flandre, CHU Lille, Avenue Eugène Avinée, 59037, Lille Cédex, France.
  • Bergounioux J; Pediatric Intensive Care Unit, AP-HP, Hôpital Raymond Poincaré, F-92380, Garches, France.
  • Mbieleu B; Pediatric Intensive Care Unit, AP-HP, Hôpital Raymond Poincaré, F-92380, Garches, France.
  • Rubinsztajn R; Hôpital Necker-Enfants Malades, F-75015, Paris, France.
  • Sigur E; Pediatric Pulmonology and Allergology Unit, Hôpital des Enfants, 31000, Toulouse, France.
  • Labouret G; Pediatric Pulmonology and Allergology Unit, Hôpital des Enfants, 31000, Toulouse, France.
  • Genevois A; Pediatric Pulmonology and Allergology Unit, Hôpital des Enfants, 31000, Toulouse, France.
  • Becourt A; Pediatric Pulmonology, CHU Amiens Picardie, 80054, France.
  • Hullo E; Pediatric Pulmonology Unit, Hôpital Couple-Enfant, CHU Grenoble, 38000, Grenoble, France.
  • Pin I; Pediatric Pulmonology Unit, Hôpital Couple-Enfant, CHU Grenoble, 38000, Grenoble, France; INSERM, Institute for Advanced Biosciences, 38000, Grenoble, France; Grenoble Alpes University, 38000, Grenoble, France.
  • Debelleix S; Pediatric Pulmonology Unit, Hôpital Pellegrin-Enfants, CIC-P Bordeaux 1401, CHU de Bordeaux, 33076, Bordeaux, France.
  • Galodé F; Pediatric Pulmonology Unit, Hôpital Pellegrin-Enfants, CIC-P Bordeaux 1401, CHU de Bordeaux, 33076, Bordeaux, France.
  • Bui S; Pediatric Pulmonology Unit, Hôpital Pellegrin-Enfants, CIC-P Bordeaux 1401, CHU de Bordeaux, 33076, Bordeaux, France.
  • Moreau J; Pediatric Cardiology and Pulmonology Department, Montpellier University Hospital, 34000, Montpellier, France; Physiology and Experimental Biology of Heart and Muscles Laboratory-PHYMEDEXP, UMR CNRS 9214, INSERM U1046, University of Montpellier, 34000, Montpellier, France.
  • Renoux MC; Pediatric Cardiology and Pulmonology Department, Montpellier University Hospital, 34000, Montpellier, France.
  • Matecki S; Pediatric Cardiology and Pulmonology Department, Montpellier University Hospital, 34000, Montpellier, France; Functional Exploration Laboratory, Physiology Department, University Hospital, 34000, Montpellier, France.
  • Lavadera ML; Respiratory Diseases, Allergy and CF Unit, Pediatric Department, University Hospital Charles Nicolle, 76000, Rouen, France.
  • Heyman R; Pediatric Unit, Department of Physical Medicine and Rehabilitation, Hôpital Pontchaillou, Rennes, 35033, Rennes, France.
  • Pomedio M; Pediatric Intensive Care Unit, American Memorial Hospital, CHU Reims, 51000, Reims, France.
  • Le Clainche L; Pediatric Noninvasive Ventilation, AP-HP, Hôpital Robert Debré, F-75018, Paris, France.
  • Bokov P; Pediatric Noninvasive Ventilation, AP-HP, Hôpital Robert Debré, F-75018, Paris, France.
  • Masson A; Pediatric Unit, Hôpital de la Mère et de l'Enfant, 87042, Limoges, France.
  • Hangard P; Pediatric Unit, Hôpital de la Mère et de l'Enfant, 87042, Limoges, France.
  • Menetrey C; Pediatric Unit, Hôpital de la Mère et de l'Enfant, 87042, Limoges, France.
  • Jokic M; Pediatric Intensive Care Unit, CHU de Caen Normandie, 14033, Caen, France.
  • Gachelin E; Pediatric Department, CHU Félix Guyon, F-97404, Saint Denis, La Réunion, France.
  • Perisson C; Pediatric Department, CHU Sud Réunion, F-97448, Saint Pierre, La Réunion, France.
  • Pervillé A; Hôpital d'Enfants - ASFA, F-97404, Saint Denis, La Réunion, France.
  • Fina A; Pediatric Pulmonology and Allergology Department, Hôpitaux Pédiatriques de Nice CHU-Lenval, Nice, France.
  • Giovannini-Chami L; Pediatric Pulmonology and Allergology Department, Hôpitaux Pédiatriques de Nice CHU-Lenval, Nice, France.
  • Fleurence E; ESEAN-APF, Health Center for Children and Adolescents, 44200, Nantes, France.
  • Barzic A; Pediatric Department, CHU Brest, 29200, Brest, France.
  • Breining A; Pediatric Department, CHU Strasbourg, 67000, Strasbourg, France.
  • Ollivier M; Pediatric Intensive Care Unit, CHU Angers, 49100, Angers, France.
  • Labbé G; Pediatric Pulmonology and Allergology Unit, CHU d'Estaing, 63003, Clermont-Ferrand, France.
  • Coutier L; Paediatric Intensive Care Unit, Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant, 69677, Bron, France.
  • Aubertin G; Pediatric Pulmonology and Allergology Unit, Hospices Civils de Lyon, 69677, Bron, France; Sorbonne Université, INSERM UMR-S 938, Centre de Recherche Saint-Antoine (CRSA), F-75014, Paris, France; Centre de Pneumologie de l'enfant, Ramsay Générale de Santé, 92100, Boulogne-Billancourt, France.
Respir Med ; 181: 106388, 2021 05.
Article in En | MEDLINE | ID: mdl-33848922
ABSTRACT

OBJECTIVE:

To describe the characteristics of children treated with long term continuous positive airway pressure (CPAP) or noninvasive ventilation (NIV) in France.

DESIGN:

Cross-sectional national survey.

SETTING:

Paediatric CPAP/NIV teams of 28 tertiary university hospitals in France. PATIENTS Children aged <20 years treated with CPAP/NIV since at least 3 months on June 1st, 2019. INTERVENTION An anonymous questionnaire was filled in for every patient.

RESULTS:

The data of 1447 patients (60% boys), mean age 9.8 ± 5.8 years were analysed. The most frequent underlying disorders were upper airway obstruction (46%), neuromuscular disease (28%), disorder of the central nervous system (13%), cardiorespiratory disorder (7%), and congenital bone disease (4%). Forty-five percent of the patients were treated with CPAP and 55% with NIV. Treatment was initiated electively for 92% of children, while 8% started during an acute illness. A poly(somno)graphy (P(S)G) was performed prior to treatment initiation in 26%, 36% had a P(S)G with transcutaneous carbon dioxide monitoring (PtcCO2), while 23% had only a pulse oximetry (SpO2) with PtcCO2 recording. The decision of CPAP/NIV initiation during an elective setting was based on the apnea-hypopnea index (AHI) in 41% of patients, SpO2 and PtcCO2 in 25% of patients, and AHI with PtcCO2 in 25% of patients. Objective adherence was excellent with a mean use of 7.6 ± 3.2 h/night. Duration of CPAP/NIV was 2.7 ± 2.9 years at the time of the survey.

CONCLUSION:

This survey shows the large number of children treated with long term CPAP/NIV in France with numerous children having disorders other than neuromuscular diseases.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Continuous Positive Airway Pressure / Noninvasive Ventilation Type of study: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: Europa Language: En Journal: Respir Med Year: 2021 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Continuous Positive Airway Pressure / Noninvasive Ventilation Type of study: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: Europa Language: En Journal: Respir Med Year: 2021 Document type: Article