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PdCl2-catalyzed synthesis of a new class of isocoumarin derivatives containing aminosulfonyl / aminocarboxamide moiety: First identification of a isocoumarin based PDE4 inhibitor.
Thirupataiah, B; Mounika, Guntipally; Reddy, Gangireddy Sujeevan; Kumar, Jetta Sandeep; Hossain, Kazi Amirul; Medishetti, Raghavender; Samarpita, Snigdha; Rasool, Mahaboobkhan; Mudgal, Jayesh; Mathew, Jessy E; Shenoy, Gautham G; Rao, C Mallikarjuna; Chatti, Kiranam; Parsa, Kishore V L; Pal, Manojit.
Affiliation
  • Thirupataiah B; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
  • Mounika G; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India.
  • Reddy GS; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
  • Kumar JS; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
  • Hossain KA; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India.
  • Medishetti R; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
  • Samarpita S; Immunopathology Lab, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, India.
  • Rasool M; Immunopathology Lab, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, India.
  • Mudgal J; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
  • Mathew JE; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
  • Shenoy GG; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
  • Rao CM; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, Manipal, 576 104, Karnataka, India.
  • Chatti K; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India.
  • Parsa KVL; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India.
  • Pal M; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, 500 046, India. Electronic address: manojitpal@rediffmail.com.
Eur J Med Chem ; 221: 113514, 2021 Oct 05.
Article in En | MEDLINE | ID: mdl-33992926

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Experimental / Sulfonamides / Isocoumarins / Phosphodiesterase 4 Inhibitors / Anti-Inflammatory Agents Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Eur J Med Chem Year: 2021 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Experimental / Sulfonamides / Isocoumarins / Phosphodiesterase 4 Inhibitors / Anti-Inflammatory Agents Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Eur J Med Chem Year: 2021 Document type: Article Affiliation country: