Immunoglobulin Y for Potential Diagnostic and Therapeutic Applications in Infectious Diseases.
Front Immunol
; 12: 696003, 2021.
Article
in En
| MEDLINE
| ID: mdl-34177963
ABSTRACT
Antiviral, antibacterial, and antiparasitic drugs and vaccines are essential to maintaining the health of humans and animals. Yet, their production can be slow and expensive, and efficacy lost once pathogens mount resistance. Chicken immunoglobulin Y (IgY) is a highly conserved homolog of human immunoglobulin G (IgG) that has shown benefits and a favorable safety profile, primarily in animal models of human infectious diseases. IgY is fast-acting, easy to produce, and low cost. IgY antibodies can readily be generated in large quantities with minimal environmental harm or infrastructure investment by using egg-laying hens. We summarize a variety of IgY uses, focusing on their potential for the detection, prevention, and treatment of human and animal infections.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Parasitic Diseases
/
Bacterial Infections
/
Virus Diseases
/
Immunoglobulins
/
Immunoassay
/
Chickens
/
Antibodies, Neutralizing
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Front Immunol
Year:
2021
Document type:
Article
Affiliation country: