ANO1; ANO1, anoctamin-1; ASM, airway smooth muscle; Ang II, angiotensin II; BBB, blood­brain barrier; CAMK, Ca2+/calmodulin-dependent protein kinase; CF, cystic fibrosis; CFTR, cystic fibrosis transmembrane conductance regulator; Ca2+-activated Cl­ channels (CaCCs); CaCCinh-A01; CaCCs, Ca2+ activated chloride channels; Cancer; Cystic fibrosis; DRG, dorsal root ganglion; Drug target; EGFR, epidermal growth factor receptor; ENaC, epithelial sodium channels; ER, endoplasmic reticulum; ESCC, esophageal squamous cell carcinoma; FRT, fisher rat thyroid; GI, gastrointestinal; GIST, gastrointestinal stromal tumor; GPCR, G-protein coupled receptor; HNSCC, head and neck squamous cell carcinoma; HTS, high-throughput screening; ICC, interstitial cells of Cajal; IPAH, idiopathic pulmonary arterial hypertension; MAPK, mitogen-activated protein kinase; NF-κB, nuclear factor κB; PAH, pulmonary arterial hypertension; PAR2, protease activated receptor 2; PASMC, pulmonary artery smooth muscle cells; PIP2, phosphatidylinositol 4,5-bisphosphate; PKD, polycystic kidney disease; T16Ainh-A01; TGF-ß, transforming growth factor-ß; TMEM16A; VGCC, voltage gated calcium channel; VRAC, volume regulated anion channel; VSMC, vascular smooth muscle cells; YFP, yellow fluorescent protein