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Tumor microenvironment in giant cell tumor of bone: evaluation of PD-L1 expression and SIRPα infiltration after denosumab treatment.
Toda, Yu; Kohashi, Kenichi; Yamamoto, Hidetaka; Ishihara, Shin; Ito, Yoshihiro; Susuki, Yosuke; Kawaguchi, Kengo; Kiyozawa, Daisuke; Takamatsu, Dai; Kinoshita, Izumi; Yamada, Yuichi; Maehara, Junki; Kimura, Atsushi; Tamiya, Sadafumi; Taguchi, Kenichi; Matsunobu, Tomoya; Matsumoto, Yoshihiro; Nakashima, Yasuharu; Mawatari, Masaaki; Oda, Yoshinao.
Affiliation
  • Toda Y; Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Kohashi K; Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Yamamoto H; Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Ishihara S; Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Ito Y; Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Susuki Y; Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Kawaguchi K; Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Kiyozawa D; Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Takamatsu D; Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Kinoshita I; Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Yamada Y; Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Maehara J; Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Kimura A; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Tamiya S; Department of Pathology, Kitakyushu Municipal Medical Center, Fukuoka, Japan.
  • Taguchi K; Department of Pathology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan.
  • Matsunobu T; Department of Orthopaedic Surgery, Kyushu Rosai Hospital, Fukuoka, Japan.
  • Matsumoto Y; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Nakashima Y; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Mawatari M; Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, Saga, Japan.
  • Oda Y; Department of Anatomic Pathology, Pathological Sciences, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka, 812-8582, Japan. oda@surgpath.med.kyushu-u.ac.jp.
Sci Rep ; 11(1): 14821, 2021 07 20.
Article in En | MEDLINE | ID: mdl-34285260
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Neoplasms / Receptors, Immunologic / Antigens, Differentiation / Giant Cell Tumor of Bone / B7-H1 Antigen / Denosumab Type of study: Observational_studies Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Sci Rep Year: 2021 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Neoplasms / Receptors, Immunologic / Antigens, Differentiation / Giant Cell Tumor of Bone / B7-H1 Antigen / Denosumab Type of study: Observational_studies Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Sci Rep Year: 2021 Document type: Article Affiliation country: Country of publication: