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A third-generation mouse model of Alzheimer's disease shows early and increased cored plaque pathology composed of wild-type human amyloid ß peptide.
Sato, Kaori; Watamura, Naoto; Fujioka, Ryo; Mihira, Naomi; Sekiguchi, Misaki; Nagata, Kenichi; Ohshima, Toshio; Saito, Takashi; Saido, Takaomi C; Sasaguri, Hiroki.
Affiliation
  • Sato K; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako, Saitama, Japan; Laboratory for Molecular Brain Science, Department of Life Science and Medical Bioscience, Waseda University, Shinjuku, Tokyo, Japan.
  • Watamura N; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako, Saitama, Japan.
  • Fujioka R; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako, Saitama, Japan.
  • Mihira N; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako, Saitama, Japan.
  • Sekiguchi M; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako, Saitama, Japan.
  • Nagata K; Department of Functional Anatomy and Neuroscience, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.
  • Ohshima T; Laboratory for Molecular Brain Science, Department of Life Science and Medical Bioscience, Waseda University, Shinjuku, Tokyo, Japan.
  • Saito T; Department of Neurocognitive Science, Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan.
  • Saido TC; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako, Saitama, Japan. Electronic address: takaomi.saido@riken.jp.
  • Sasaguri H; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako, Saitama, Japan. Electronic address: hiroki.sasaguri@riken.jp.
J Biol Chem ; 297(3): 101004, 2021 09.
Article in En | MEDLINE | ID: mdl-34329683
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Amyloid beta-Peptides / Plaque, Amyloid / Disease Models, Animal / Alzheimer Disease Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2021 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Amyloid beta-Peptides / Plaque, Amyloid / Disease Models, Animal / Alzheimer Disease Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2021 Document type: Article Affiliation country: Country of publication: