Lymphadenopathy after the Anti-COVID-19 Vaccine: Multiparametric Ultrasound Findings.
Biology (Basel)
; 10(7)2021 Jul 12.
Article
in En
| MEDLINE
| ID: mdl-34356507
ABSTRACT
Background:
Post-anti-COVID-19 vaccine lymphadenopathy has recently been described in the literature. In this study, we investigated the multiparametric US findings of patients with post-vaccine lymphadenopathy and compared these findings among different anti-COVID-19 vaccines.Methods:
We retrospectively evaluated 24 patients who underwent US between January and May 2021 due to post-anti-COVID-19 lymphadenopathy. The presence, size, location, number, morphology, cortex-hilum, superb microvascular imaging (SMI) and elastosonography of lymph nodes were assessed. Descriptive statistics were calculated and differences among anti-COVID-19 vaccines were analyzed using the Kruskal-Wallis test. A p-value ≤ 0.05 was considered statistically significant.Results:
Sixty-six nodes were assessed. They were axillary (mean 1.6 cm ± 0.16) in 11 patients (45.8%) and supraclavicular (mean 0.9 cm ± 0.19) in 13 patients (54.2%). In 20 patients (83.3%), the number of nodes was ≤3. Prevalent US features included oval morphology (18, 75%), asymmetric cortex with hilum evidence (9, 37.5%), central and peripheral vascular signals (12, 50%) at SMI and elastosonography patterns similar to the surrounding tissue (15, 71.4%). No significant differences among the three anti-COVID-19 vaccines were observed (p > 0.05).Conclusions:
Anti-COVID-19 vaccines may present lymphadenopathy with "worrisome" US features regarding size, shape, morphology, cortex-hilum, SMI and elastosonography. An awareness of the patient's history and US findings may help in the early recognition of this clinical scenario and in the appropriate selection of patients for a short-term US follow-up.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Type of study:
Diagnostic_studies
Language:
En
Journal:
Biology (Basel)
Year:
2021
Document type:
Article
Affiliation country:
Publication country:
CH
/
SUIZA
/
SUÍÇA
/
SWITZERLAND