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PCC-0105002, a novel small molecule inhibitor of PSD95-nNOS protein-protein interactions, attenuates neuropathic pain and corrects motor disorder associated with neuropathic pain model.
Sun, Zhihong; Meng, Ping; Su, Chunyu; Ji, Shengmin; Gao, Yonglin; Wang, Hongbo; Tian, Jingwei; Li, Chunmei.
Affiliation
  • Sun Z; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, China.
  • Meng P; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, China.
  • Su C; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, China.
  • Ji S; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, China.
  • Gao Y; School of Life Science, Yantai University, Yantai 264005, China.
  • Wang H; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, China.
  • Tian J; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, China. Electronic address: tianjingw
  • Li C; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, China. Electronic address: gaoyongli
Toxicol Appl Pharmacol ; 429: 115698, 2021 10 15.
Article in En | MEDLINE | ID: mdl-34428447

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Nerves / Posterior Horn Cells / Esters / Nitric Oxide Synthase Type I / Disks Large Homolog 4 Protein / Aminobenzoates / Analgesics / Motor Activity / Neuralgia Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2021 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Nerves / Posterior Horn Cells / Esters / Nitric Oxide Synthase Type I / Disks Large Homolog 4 Protein / Aminobenzoates / Analgesics / Motor Activity / Neuralgia Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2021 Document type: Article Affiliation country: