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Curcumenol mitigates chondrocyte inflammation by inhibiting the NF­κB and MAPK pathways, and ameliorates DMM­induced OA in mice.
Yang, Xiao; Zhou, Yifan; Chen, Zhiqian; Chen, Chen; Han, Chen; Li, Xunlin; Tian, Haijun; Cheng, Xiaofei; Zhang, Kai; Zhou, Tangjun; Zhao, Jie.
Affiliation
  • Yang X; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, P.R. China.
  • Zhou Y; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, P.R. China.
  • Chen Z; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, P.R. China.
  • Chen C; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, P.R. China.
  • Han C; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, P.R. China.
  • Li X; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, P.R. China.
  • Tian H; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, P.R. China.
  • Cheng X; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, P.R. China.
  • Zhang K; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, P.R. China.
  • Zhou T; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, P.R. China.
  • Zhao J; Shanghai Key Laboratory of Orthopedic Implants, Department of Orthopedics, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, P.R. China.
Int J Mol Med ; 48(4)2021 10.
Article in En | MEDLINE | ID: mdl-34435650
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Sesquiterpenes / Menisci, Tibial / NF-kappa B / Chondrocytes / Mitogen-Activated Protein Kinases / Inflammation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Int J Mol Med Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2021 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Sesquiterpenes / Menisci, Tibial / NF-kappa B / Chondrocytes / Mitogen-Activated Protein Kinases / Inflammation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Int J Mol Med Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2021 Document type: Article Country of publication: