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Progressive endoplasmic reticulum stress over time due to human insulin gene mutation contributes to pancreatic beta cell dysfunction.
Amirruddin, Nur Shabrina; Tan, Wei Xuan; Tan, Yaw Sing; Gardner, Daphne Su-Lyn; Bee, Yong Mong; Verma, Chandra Shekhar; Hoon, Shawn; Lee, Kok Onn; Teo, Adrian Kee Keong.
Affiliation
  • Amirruddin NS; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore.
  • Tan WX; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore.
  • Tan YS; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore.
  • Gardner DS; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore.
  • Bee YM; Bioinformatics Institute, A*STAR, Singapore, Republic of Singapore.
  • Verma CS; Department of Endocrinology, Singapore General Hospital, Singapore, Republic of Singapore.
  • Hoon S; Department of Endocrinology, Singapore General Hospital, Singapore, Republic of Singapore.
  • Lee KO; Bioinformatics Institute, A*STAR, Singapore, Republic of Singapore.
  • Teo AKK; Department of Biological Sciences, National University of Singapore, Singapore, Republic of Singapore.
Diabetologia ; 64(11): 2534-2549, 2021 11.
Article in En | MEDLINE | ID: mdl-34448879

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Diseases / Insulin-Secreting Cells / Endoplasmic Reticulum Stress / Insulin / Mutation Limits: Humans / Infant Language: En Journal: Diabetologia Year: 2021 Document type: Article Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Diseases / Insulin-Secreting Cells / Endoplasmic Reticulum Stress / Insulin / Mutation Limits: Humans / Infant Language: En Journal: Diabetologia Year: 2021 Document type: Article Country of publication: