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The Ile191Val is a partial loss-of-function variant of the TAS1R2 sweet-taste receptor and is associated with reduced glucose excursions in humans.
Serrano, Joan; Seflova, Jaroslava; Park, Jihye; Pribadi, Marsha; Sanematsu, Keisuke; Shigemura, Noriatsu; Serna, Vanida; Yi, Fanchao; Mari, Andrea; Procko, Erik; Pratley, Richard E; Robia, Seth L; Kyriazis, George A.
Affiliation
  • Serrano J; Department of Biological Chemistry & Pharmacology, College of Medicine, The Ohio State University, Columbus, OH, USA.
  • Seflova J; Department of Cell and Molecular Physiology, Loyola University Chicago, Maywood, IL, 60153, USA.
  • Park J; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
  • Pribadi M; Department of Cell and Molecular Physiology, Loyola University Chicago, Maywood, IL, 60153, USA.
  • Sanematsu K; Section of Oral Neuroscience, Graduate School of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Shigemura N; Section of Oral Neuroscience, Graduate School of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Serna V; Department of Biological Chemistry & Pharmacology, College of Medicine, The Ohio State University, Columbus, OH, USA.
  • Yi F; AdventHealth Translational Research Institute, Orlando, FL, 32804, USA.
  • Mari A; Institute of Neuroscience, National Research Council, Padova, Italy.
  • Procko E; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
  • Pratley RE; AdventHealth Translational Research Institute, Orlando, FL, 32804, USA.
  • Robia SL; Department of Cell and Molecular Physiology, Loyola University Chicago, Maywood, IL, 60153, USA.
  • Kyriazis GA; Department of Biological Chemistry & Pharmacology, College of Medicine, The Ohio State University, Columbus, OH, USA. Electronic address: Georgios.Kyriazis@osumc.edu.
Mol Metab ; 54: 101339, 2021 12.
Article in En | MEDLINE | ID: mdl-34509698
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Taste / Receptors, G-Protein-Coupled / Glucose Type of study: Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: Mol Metab Year: 2021 Document type: Article Affiliation country: Country of publication:
Fulltext
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Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Taste / Receptors, G-Protein-Coupled / Glucose Type of study: Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: Mol Metab Year: 2021 Document type: Article Affiliation country: Country of publication: