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Minimal clinically important difference of modified dynamic gait index in people with neurological disorders.
Corrini, Chiara; Torchio, Alessandro; Anastasi, Denise; Parelli, Riccardo; Meotti, Matteo; Spedicato, Albino; Groppo, Elisabetta; D'Arma, Alessia; Grosso, Cristina; Montesano, Angelo; Cattaneo, Davide; Gervasoni, Elisa.
Affiliation
  • Corrini C; IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
  • Torchio A; IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
  • Anastasi D; IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
  • Parelli R; IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
  • Meotti M; IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
  • Spedicato A; IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
  • Groppo E; U.O. Clinica Neurologica, III Ospedale San Paolo Via Antonio di Rudini 8, 20142, Milano, Italy.
  • D'Arma A; IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
  • Grosso C; IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
  • Montesano A; IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
  • Cattaneo D; IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy; Department of Pathophysiology and Transplantation, University of Milan 20100, Milan, Italy. Electronic address: dcattaneo@dongnocchi.it.
  • Gervasoni E; IRCSS Fondazione Don Carlo Gnocchi, Via Capecelatro, 66-20148, Milano, Italy.
Gait Posture ; 90: 210-214, 2021 10.
Article in En | MEDLINE | ID: mdl-34509972
ABSTRACT

BACKGROUND:

The minimal clinically important difference (MCID) of modified Dynamic Gait Index (mDGI) has not yet been determined for People with Neurological Disorders (PwND). RESEARCH QUESTION To establish the MCID of the mDGI to determine clinically meaningful improvement in balance and gait in PwND.

METHODS:

In this longitudinal study from a randomised clinical trial, 55 participants both in and outpatients with neurological disorders, received fifteen 40-minute rehabilitation sessions. Inpatients received daily treatments over a period of three weeks while outpatients received three treatments/week over a period of five weeks. An anchor-based method using percentage rating of improvement in balance (Activities Balance Confidence scale, ABC) was used to determine the MCID of mDGI. The MCID was defined as the minimum change in mDGI total score (post - pre intervention) that was needed to perceive at least a 10 % improvement on the ABC scale. A Receiver Operating Characteristic curve was used to define the cut-off for the optimal MCID of the mDGI discriminating between improved and not improved participants.

RESULTS:

The MCID of the mDGI total score was 6 points and Area under the Curve was 0.64. For the mDGI time sub-scores the MCID was 2 points and Area under the Curve was 0.6.

SIGNIFICANCE:

The MCID of balance and gait improvement measured by mDGI was prudently establish at ≥7 points, meaning that this is the minimum improvement score PwND need to get to perceive a clinically relevant change in their balance and gait confidence. These reference values can be a tool incorporated into clinicians daily practice to interpret mDGI change scores helping to determine whether the intervention is effective; to develop clinical tailored intervention goals and to establish meaningful perceived change in PwND.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Minimal Clinically Important Difference / Nervous System Diseases Type of study: Clinical_trials / Observational_studies / Prognostic_studies Limits: Humans Language: En Journal: Gait Posture Journal subject: ORTOPEDIA Year: 2021 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Minimal Clinically Important Difference / Nervous System Diseases Type of study: Clinical_trials / Observational_studies / Prognostic_studies Limits: Humans Language: En Journal: Gait Posture Journal subject: ORTOPEDIA Year: 2021 Document type: Article Affiliation country: