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NAD+ flux is maintained in aged mice despite lower tissue concentrations.
McReynolds, Melanie R; Chellappa, Karthikeyani; Chiles, Eric; Jankowski, Connor; Shen, Yihui; Chen, Li; Descamps, Hélène C; Mukherjee, Sarmistha; Bhat, Yashaswini R; Lingala, Siddharth R; Chu, Qingwei; Botolin, Paul; Hayat, Faisal; Doke, Tomohito; Susztak, Katalin; Thaiss, Christoph A; Lu, Wenyun; Migaud, Marie E; Su, Xiaoyang; Rabinowitz, Joshua D; Baur, Joseph A.
Affiliation
  • McReynolds MR; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA; Department of Chemistry, Princeton University, Princeton, NJ, USA.
  • Chellappa K; Department of Physiology and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Chiles E; Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA.
  • Jankowski C; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.
  • Shen Y; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA; Department of Chemistry, Princeton University, Princeton, NJ, USA.
  • Chen L; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA; Department of Chemistry, Princeton University, Princeton, NJ, USA.
  • Descamps HC; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Mukherjee S; Department of Physiology and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Bhat YR; Department of Physiology and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Lingala SR; Department of Physiology and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Chu Q; Department of Physiology and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Botolin P; Department of Physiology and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Hayat F; Department of Pharmacology, Mitchell Cancer Institute, College of Medicine, University of South Alabama, Mobile, AL, USA.
  • Doke T; Department of Medicine, Renal Electrolyte and Hypertension Division, University of Pennsylvania, Philadelphia, PA, USA.
  • Susztak K; Department of Medicine, Renal Electrolyte and Hypertension Division, University of Pennsylvania, Philadelphia, PA, USA.
  • Thaiss CA; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Lu W; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA; Department of Chemistry, Princeton University, Princeton, NJ, USA.
  • Migaud ME; Department of Pharmacology, Mitchell Cancer Institute, College of Medicine, University of South Alabama, Mobile, AL, USA.
  • Su X; Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ, USA.
  • Rabinowitz JD; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA; Department of Chemistry, Princeton University, Princeton, NJ, USA. Electronic address: joshr@princeton.edu.
  • Baur JA; Department of Physiology and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: baur@pennmedicine.upenn.edu.
Cell Syst ; 12(12): 1160-1172.e4, 2021 12 15.
Article in En | MEDLINE | ID: mdl-34559996
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Niacinamide / NAD Limits: Animals Language: En Journal: Cell Syst Year: 2021 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Niacinamide / NAD Limits: Animals Language: En Journal: Cell Syst Year: 2021 Document type: Article Affiliation country: