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Development of a one-step RT-ddPCR method to determine the expression and potency of AAV vectors.
Clarner, Pete; Lau, Shukkwan K; Chowdhury, Twinkle; Guilmette, Edward; Trapa, Patrick; Lo, Shih-Ching; Shen, Shen.
Affiliation
  • Clarner P; Gene Therapy Accelerator Unit, Biotherapeutic and Medicinal Sciences, Biogen, 225 Binney Street, Cambridge, MA 02142, USA.
  • Lau SK; Neuromuscular and Muscle Disorders Research Unit, Research, Biogen, 225 Binney Street, Cambridge, MA 02142, USA.
  • Chowdhury T; Neuromuscular and Muscle Disorders Research Unit, Research, Biogen, 225 Binney Street, Cambridge, MA 02142, USA.
  • Guilmette E; Gene Therapy Accelerator Unit, Biotherapeutic and Medicinal Sciences, Biogen, 225 Binney Street, Cambridge, MA 02142, USA.
  • Trapa P; Drug Metabolism and Pharmacokinetics, Biotherapeutic and Medicinal Sciences, Biogen, 225 Binney Street, Cambridge, MA 02142, USA.
  • Lo SC; Neuromuscular and Muscle Disorders Research Unit, Research, Biogen, 225 Binney Street, Cambridge, MA 02142, USA.
  • Shen S; Gene Therapy Accelerator Unit, Biotherapeutic and Medicinal Sciences, Biogen, 225 Binney Street, Cambridge, MA 02142, USA.
Mol Ther Methods Clin Dev ; 23: 68-77, 2021 Dec 10.
Article in En | MEDLINE | ID: mdl-34589555

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Mol Ther Methods Clin Dev Year: 2021 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Mol Ther Methods Clin Dev Year: 2021 Document type: Article Affiliation country: Country of publication: