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Cholesterol biosynthesis inhibitor RO 48­8071 inhibits pancreatic ductal adenocarcinoma cell viability by deactivating the JNK and ERK/MAPK signaling pathway.
Ding, Zhen; Gu, Yanan; Huang, Dake; Zhou, Hong; Zhu, Tingting; Luo, Xin; Zhang, Sumei; Zhang, Shengquan; Qian, Yeben.
Affiliation
  • Ding Z; Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China.
  • Gu Y; Department of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
  • Huang D; Comprehensive Laboratory, School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
  • Zhou H; Department of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
  • Zhu T; Department of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
  • Luo X; Department of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
  • Zhang S; Department of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
  • Zhang S; Department of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, Anhui 230032, P.R. China.
  • Qian Y; Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China.
Mol Med Rep ; 24(6)2021 12.
Article in En | MEDLINE | ID: mdl-34590153
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzophenones / MAP Kinase Signaling System / Carcinoma, Pancreatic Ductal / Cell Proliferation / Lipid Metabolism / Cell Cycle Checkpoints Limits: Animals / Humans / Male Language: En Journal: Mol Med Rep Year: 2021 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzophenones / MAP Kinase Signaling System / Carcinoma, Pancreatic Ductal / Cell Proliferation / Lipid Metabolism / Cell Cycle Checkpoints Limits: Animals / Humans / Male Language: En Journal: Mol Med Rep Year: 2021 Document type: Article Country of publication: