Therapeutic effects of green tea on endometriosis.
Crit Rev Food Sci Nutr
; 63(18): 3222-3235, 2023.
Article
in En
| MEDLINE
| ID: mdl-34620005
ABSTRACT
Endometriosis is a chronic disorder characterized by the presence of endometrial glands and stroma outside the uterine cavity. It affects 8%-10% of women in their reproductive years, and represents a major clinical problem with deleterious social, sexual and reproductive consequences. Current treatment options include pain relief, hormonal intervention and surgical removal. However, these treatments are deemed unsatisfactory owing to varying success, significant side effects and high recurrence rates. Green tea and its major bioactive component, (-)-epigallocatechin gallate (EGCG), possess diverse biological properties, particularly anti-angiogenic, anti-proliferation, anti-metastasis, and apoptosis induction. In recent years, preclinical studies have proposed the use of green tea to inhibit the growth of endometriosis. Herein, the aim of this review is to summarize the potential therapeutic effects of green tea on molecular and cellular mechanism through inflammation, oxidative stress, invasion and adhesion, apoptosis and angiogenesis in endometriosis.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Catechin
/
Endometriosis
Limits:
Female
/
Humans
Language:
En
Journal:
Crit Rev Food Sci Nutr
Journal subject:
CIENCIAS DA NUTRICAO
Year:
2023
Document type:
Article
Affiliation country: