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Design, parallel synthesis of Biginelli 1,4-dihydropyrimidines using PTSA as a catalyst, evaluation of anticancer activity and structure activity relationships via 3D QSAR studies.
Faizan, Syed; Prashantha Kumar, B R; Lalitha Naishima, Namburu; Ashok, T; Justin, Antony; Vijay Kumar, Merugumolu; Bistuvalli Chandrashekarappa, Revanasiddappa; Manjunathaiah Raghavendra, Nulgumnalli; Kabadi, Pradeep; Adhikary, Laxmi.
Affiliation
  • Faizan S; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Mysuru 570 015, Constituent College of JSS Academy of Higher Education & Research, Mysuru 570 015. India.
  • Prashantha Kumar BR; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Mysuru 570 015, Constituent College of JSS Academy of Higher Education & Research, Mysuru 570 015. India.
  • Lalitha Naishima N; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Mysuru 570 015, Constituent College of JSS Academy of Higher Education & Research, Mysuru 570 015. India.
  • Ashok T; Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Mysuru 570 015, Constituent College of JSS Academy of Higher Education & Research, Mysuru 570 015. India.
  • Justin A; Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty 643 001, Nilgiris, Tamil Nadu, India.
  • Vijay Kumar M; NGSM Institute of Pharmaceutical Sciences (NGSMIPS), Nitte (Deemed to be University), Mangalore 575018, Karnataka, India.
  • Bistuvalli Chandrashekarappa R; NGSM Institute of Pharmaceutical Sciences (NGSMIPS), Nitte (Deemed to be University), Mangalore 575018, Karnataka, India.
  • Manjunathaiah Raghavendra N; Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru 560 107, India.
  • Kabadi P; Bioanalytical Division, Biocon Pvt. Ltd, Bengaluru 560 100, India.
  • Adhikary L; Bioanalytical Division, mAbxience Insud Pharma, Madrid 28050, Spain.
Bioorg Chem ; 117: 105462, 2021 12.
Article in En | MEDLINE | ID: mdl-34753059

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Drug Design / Quantitative Structure-Activity Relationship / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Chem Year: 2021 Document type: Article Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Drug Design / Quantitative Structure-Activity Relationship / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Chem Year: 2021 Document type: Article Country of publication: