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Hazelnut Shells as Source of Active Ingredients: Extracts Preparation and Characterization.
Di Michele, Alessandro; Pagano, Cinzia; Allegrini, Agnese; Blasi, Francesca; Cossignani, Lina; Raimo, Enrico Di; Faieta, Marco; Oliva, Eleonora; Pittia, Paola; Primavilla, Sara; Sergi, Manuel; Vicino, Camilla; Ricci, Maurizio; Schirone, Bartolomeo; Perioli, Luana.
Affiliation
  • Di Michele A; Department of Physics and Geology, University of Perugia, 06123 Perugia, Italy.
  • Pagano C; Department of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.
  • Allegrini A; Department of Agricolture and Forestry (DAFNE), Università degli Studi della Tuscia, Via San Camillo de Lellis, 01100 Viterbo, Italy.
  • Blasi F; Department of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.
  • Cossignani L; Department of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.
  • Raimo ED; Istituto Zooprofilattico dell'Umbria e delle Marche, Via G. Salvemini 1, 06126 Perugia, Italy.
  • Faieta M; Faculty of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Via R. Balzarini 1, 64100 Teramo, Italy.
  • Oliva E; Faculty of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Via R. Balzarini 1, 64100 Teramo, Italy.
  • Pittia P; Faculty of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Via R. Balzarini 1, 64100 Teramo, Italy.
  • Primavilla S; Istituto Zooprofilattico dell'Umbria e delle Marche, Via G. Salvemini 1, 06126 Perugia, Italy.
  • Sergi M; Faculty of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Via R. Balzarini 1, 64100 Teramo, Italy.
  • Vicino C; Department of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.
  • Ricci M; Department of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.
  • Schirone B; Department of Agricolture and Forestry (DAFNE), Università degli Studi della Tuscia, Via San Camillo de Lellis, 01100 Viterbo, Italy.
  • Perioli L; Department of Pharmaceutical Sciences, University of Perugia, 06123 Perugia, Italy.
Molecules ; 26(21)2021 Oct 31.
Article in En | MEDLINE | ID: mdl-34771017
Hazelnut shells represent a waste material (about 42% of the total biomass) deriving from hazelnut harvest. These are mainly used as a heating source; however, they represent an interesting source of polyphenols useful in health field. The impact on phenolic profile and concentrations of hazelnut shell extracts obtained by three extraction methods (maceration, ultrasonic bath, and high-power ultrasonic), as well as temperature, extraction time, and preventive maceration, was studied. The prepared extracts were characterized in terms of chemical composition, antioxidant and antimicrobial activities. Eighteen different phenolic compounds were identified and quantified by chemical analysis and gallic acid was the most abundant in all the extracts analyzed. Other relevant compounds were chlorogenic acid, protocatechuic acid and catechin. Preventive maceration had a positive effect on the extraction of different types of compounds regardless of the method performed. Application of the high-power ultrasonic method had different effects, either positive or negative, depending on the type of compound and extraction time. All the prepared extracts showed antioxidant activity especially those prepared by maceration, and many of them were able to inhibit the growth of both B. subtilis and B. cereus.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacillus cereus / Bacillus subtilis / Plant Extracts / Corylus / Anti-Bacterial Agents / Antioxidants Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2021 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacillus cereus / Bacillus subtilis / Plant Extracts / Corylus / Anti-Bacterial Agents / Antioxidants Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2021 Document type: Article Affiliation country: Country of publication: