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Methotrexate treatment suppresses osteoblastic differentiation by inducing Notch2 signaling and blockade of Notch2 rescues osteogenesis by preserving Wnt/ß-catenin signaling.
Peymanfar, Yaser; Su, Yu-Wen; Hassanshahi, Mohammadhossein; Xian, Cory J.
Affiliation
  • Peymanfar Y; UniSA Clinical and Health Sciences, University of South Australia, Adelaide, South Australia, Australia.
  • Su YW; UniSA Clinical and Health Sciences, University of South Australia, Adelaide, South Australia, Australia.
  • Hassanshahi M; UniSA Clinical and Health Sciences, University of South Australia, Adelaide, South Australia, Australia.
  • Xian CJ; UniSA Clinical and Health Sciences, University of South Australia, Adelaide, South Australia, Australia.
J Orthop Res ; 40(10): 2258-2270, 2022 10.
Article in En | MEDLINE | ID: mdl-34935186
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteogenesis / Beta Catenin Language: En Journal: J Orthop Res Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteogenesis / Beta Catenin Language: En Journal: J Orthop Res Year: 2022 Document type: Article Affiliation country: Country of publication: