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Quantification of succinic acid levels, linked to succinate dehydrogenase (SDH) dysfunctions, by an automated and fully validated liquid chromatography tandem mass spectrometry method suitable for multi-matrix applications.
Lamy, Constance; Mansard, Clémence; Blondel, Louis; Mercier, Lionel; Paci, Angelo; Broutin, Sophie.
Affiliation
  • Lamy C; Gustave Roussy, Service de Pharmacologie, Département de biologie et pathologie médicales, F-94805 Villejuif, France; Université Paris-Saclay, Gustave Roussy, INSERM1030, Radiothérapie moléculaire et innovation thérapeutique, F-94805 Villejuif, France.
  • Mansard C; Gustave Roussy, Service de Pharmacologie, Département de biologie et pathologie médicales, F-94805 Villejuif, France.
  • Blondel L; Gustave Roussy, Service de Pharmacologie, Département de biologie et pathologie médicales, F-94805 Villejuif, France.
  • Mercier L; Gustave Roussy, Service de Pharmacologie, Département de biologie et pathologie médicales, F-94805 Villejuif, France.
  • Paci A; Gustave Roussy, Service de Pharmacologie, Département de biologie et pathologie médicales, F-94805 Villejuif, France; Université Paris-Saclay, Gustave Roussy, INSERM1030, Radiothérapie moléculaire et innovation thérapeutique, F-94805 Villejuif, France; Service de pharmacocinétique, Faculté de pharma
  • Broutin S; Gustave Roussy, Service de Pharmacologie, Département de biologie et pathologie médicales, F-94805 Villejuif, France; Université Paris-Saclay, Gustave Roussy, INSERM1030, Radiothérapie moléculaire et innovation thérapeutique, F-94805 Villejuif, France. Electronic address: sophie.broutin@gustaverouss
J Chromatogr B Analyt Technol Biomed Life Sci ; 1189: 123085, 2022 Jan 15.
Article in En | MEDLINE | ID: mdl-34974318
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatography, Liquid / Succinic Acid / Tandem Mass Spectrometry Type of study: Diagnostic_studies / Guideline / Prognostic_studies Limits: Humans Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatography, Liquid / Succinic Acid / Tandem Mass Spectrometry Type of study: Diagnostic_studies / Guideline / Prognostic_studies Limits: Humans Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2022 Document type: Article Affiliation country: Country of publication: