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Maternal P2X7 receptor inhibition prevents autism-like phenotype in male mouse offspring through the NLRP3-IL-1ß pathway.
Szabó, Dorottya; Tod, Pál; Gölöncsér, Flóra; Román, Viktor; Lendvai, Balázs; Otrokocsi, Lilla; Sperlágh, Beáta.
Affiliation
  • Szabó D; Laboratory of Molecular Pharmacology, Institute of Experimental Medicine, Budapest, Hungary; János Szentágothai Doctoral School, Semmelweis University, Budapest, Hungary.
  • Tod P; Laboratory of Molecular Pharmacology, Institute of Experimental Medicine, Budapest, Hungary.
  • Gölöncsér F; Laboratory of Molecular Pharmacology, Institute of Experimental Medicine, Budapest, Hungary.
  • Román V; Department of Pharmacology and Drug Safety Research, Gedeon Richter Plc., Budapest, Hungary.
  • Lendvai B; Department of Pharmacology and Drug Safety Research, Gedeon Richter Plc., Budapest, Hungary.
  • Otrokocsi L; Laboratory of Molecular Pharmacology, Institute of Experimental Medicine, Budapest, Hungary.
  • Sperlágh B; Laboratory of Molecular Pharmacology, Institute of Experimental Medicine, Budapest, Hungary; János Szentágothai Doctoral School, Semmelweis University, Budapest, Hungary. Electronic address: sperlagh@koki.hu.
Brain Behav Immun ; 101: 318-332, 2022 03.
Article in En | MEDLINE | ID: mdl-35065198
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prenatal Exposure Delayed Effects / Autistic Disorder / Receptors, Purinergic P2X7 Type of study: Guideline / Prognostic_studies Limits: Animals / Pregnancy Language: En Journal: Brain Behav Immun Journal subject: ALERGIA E IMUNOLOGIA / CEREBRO / PSICOFISIOLOGIA Year: 2022 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prenatal Exposure Delayed Effects / Autistic Disorder / Receptors, Purinergic P2X7 Type of study: Guideline / Prognostic_studies Limits: Animals / Pregnancy Language: En Journal: Brain Behav Immun Journal subject: ALERGIA E IMUNOLOGIA / CEREBRO / PSICOFISIOLOGIA Year: 2022 Document type: Article Affiliation country: Country of publication: