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Intervening pyruvate carboxylase stunts tumor growth by strengthening anti-tumor actions of tumor-associated macrophages.
Shu, Yuxin; Yang, Nanfei; Cheng, Nan; Zou, Zhengyun; Zhang, Wenlong; Bei, Yuncheng; Shi, Qian; Qin, Menghao; Zhu, Wei-Guo; Shen, Pingping.
Affiliation
  • Shu Y; State Key Laboratory of Pharmaceutical Biotechnology and The Comprehensive Cancer Center, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, School of Life Sciences, Nanjing University, Nanjing, 210023, PR China.
  • Yang N; Guangdong Key Laboratory of Genome Instability and Human Disease, Shenzhen University International Cancer Center, Department of Biochemistry and Molecular Biology, Shenzhen University, Shenzhen, 518060, PR China.
  • Cheng N; State Key Laboratory of Pharmaceutical Biotechnology and The Comprehensive Cancer Center, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, School of Life Sciences, Nanjing University, Nanjing, 210023, PR China.
  • Zou Z; State Key Laboratory of Pharmaceutical Biotechnology and The Comprehensive Cancer Center, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, School of Life Sciences, Nanjing University, Nanjing, 210023, PR China.
  • Zhang W; State Key Laboratory of Pharmaceutical Biotechnology and The Comprehensive Cancer Center, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, School of Life Sciences, Nanjing University, Nanjing, 210023, PR China.
  • Bei Y; State Key Laboratory of Pharmaceutical Biotechnology and The Comprehensive Cancer Center, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, School of Life Sciences, Nanjing University, Nanjing, 210023, PR China.
  • Shi Q; State Key Laboratory of Pharmaceutical Biotechnology and The Comprehensive Cancer Center, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, School of Life Sciences, Nanjing University, Nanjing, 210023, PR China.
  • Qin M; Department of Cellular and Integrative Physiology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA.
  • Zhu WG; State Key Laboratory of Pharmaceutical Biotechnology and The Comprehensive Cancer Center, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, School of Life Sciences, Nanjing University, Nanjing, 210023, PR China.
  • Shen P; Guangdong Key Laboratory of Genome Instability and Human Disease, Shenzhen University International Cancer Center, Department of Biochemistry and Molecular Biology, Shenzhen University, Shenzhen, 518060, PR China. zhuweiguo@szu.edu.cn.
Signal Transduct Target Ther ; 7(1): 34, 2022 02 02.
Article in En | MEDLINE | ID: mdl-35105865
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyruvate Carboxylase / Tumor-Associated Macrophages / Neoplasm Proteins / Neoplasms, Experimental Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Signal Transduct Target Ther Year: 2022 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyruvate Carboxylase / Tumor-Associated Macrophages / Neoplasm Proteins / Neoplasms, Experimental Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Signal Transduct Target Ther Year: 2022 Document type: Article