Post-transcriptional regulation of factors important for the germ line.
Curr Top Dev Biol
; 146: 49-78, 2022.
Article
in En
| MEDLINE
| ID: mdl-35152986
ABSTRACT
Echinoderms are a major model system for many general aspects of biology, including mechanisms of gene regulation. Analysis of transcriptional regulation (Gene regulatory networks, direct DNA-binding of proteins to specific cis-elements, and transgenesis) has contributed to our understanding of how an embryo works. This chapter looks at post-transcriptional gene regulation in the context of how the primordial germ cells are formed, and how the factors essential for this process are regulated. Important in echinoderms, as in many embryos, is that key steps of fate determination are made post-transcriptionally. This chapter highlights these steps uncovered in sea urchins and sea stars, and links them to a general theme of how the germ line may regulate its fate differently than many of the embryo's somatic cell lineages.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Gene Expression Regulation, Developmental
/
Embryo, Nonmammalian
Type of study:
Prognostic_studies
Limits:
Animals
Language:
En
Journal:
Curr Top Dev Biol
Year:
2022
Document type:
Article
Affiliation country: