Your browser doesn't support javascript.
loading
Photoinduced Cascade C-N/C═O Bond Formation from Bromodifluoroalkyl Reagents, Amines, and H2O via a Triple-Cleavage Process.
Zhuang, Xiaohui; Ling, Lan; Wang, Yingying; Li, Bingqian; Sun, Bin; Su, Weike; Jin, Can.
Affiliation
  • Zhuang X; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, P. R. China.
  • Ling L; College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, P. R. China.
  • Wang Y; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, P. R. China.
  • Li B; College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, P. R. China.
  • Sun B; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, P. R. China.
  • Su W; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, P. R. China.
  • Jin C; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, P. R. China.
Org Lett ; 24(8): 1668-1672, 2022 03 04.
Article in En | MEDLINE | ID: mdl-35191309
ABSTRACT
A green, sustainable, and straightforward method for the synthesis of unsymmetrical oxalamides via photoinduced C-N/C═O bond formation of bromodifluoroacetamide, amine, and H2O through a triple-cleavage process has been developed. In addition, this approach also provides access to the known bioactive compounds, and a feasible reaction mechanism is proposed. Moreover, the advantages of this transformation, including mild reaction conditions, a broad substrate scope, and operational simplicity, make this protocol attractive for further applications.
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Org Lett Journal subject: BIOQUIMICA Year: 2022 Document type: Article
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Org Lett Journal subject: BIOQUIMICA Year: 2022 Document type: Article