Anti-Tumor Active Isopropylated Fused Azaisocytosine-Containing Congeners Are Safe for Developing <i>Danio rerio</i> as Well as Red Blood Cells and Activate Apoptotic Caspases in Human Breast Carcinoma Cells.

Sztanke, Malgorzata; Rzymowska, Jolanta; Sztanke, Krzysztof

Anti-Tumor Active Isopropylated Fused Azaisocytosine-Containing Congeners Are Safe for Developing Danio rerio as Well as Red Blood Cells and Activate Apoptotic Caspases in Human Breast Carcinoma Cells.

Sztanke, Malgorzata; Rzymowska, Jolanta; Sztanke, Krzysztof.

Affiliation

Sztanke M; Chair and Department of Medical Chemistry, Medical University of Lublin, 4A Chodzki Street, 20-093 Lublin, Poland.
Rzymowska J; Department of Biology and Genetics, Medical University of Lublin, 4A Chodzki Street, 20-093 Lublin, Poland.
Sztanke K; Laboratory of Bioorganic Synthesis and Analysis, Chair and Department of Medical Chemistry, Medical University of Lublin, 4A Chodzki Street, 20-093 Lublin, Poland.

Molecules ; 27(4)2022 Feb 11.

Article in En | MEDLINE | ID: mdl-35209001

Subject(s)
Key words

apoptotic caspase activation; developmental abnormalities; hemolysis assay; in vivo zebrafish embryo acute toxicity study; isopropylated fused azaisocytosine-containing congeners; phenotypic parameters; structuretoxicity relationships

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Caspases / Cytosine / Embryo, Nonmammalian / Erythrocytes / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2022 Document type: Article Affiliation country: Country of publication:

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