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Ethnic disparities in hospitalisation and hospital-outcomes during the second wave of COVID-19 infection in east London.
Wan, Y I; Apea, V J; Dhairyawan, R; Puthucheary, Z A; Pearse, R M; Orkin, C M; Prowle, J R.
Affiliation
  • Wan YI; William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK. yize.wan@qmul.ac.uk.
  • Apea VJ; Adult Critical Care Unit, Royal London Hospital, Barts Health NHS Trust, London, E1 1FR, UK. yize.wan@qmul.ac.uk.
  • Dhairyawan R; Blizard Institute, Queen Mary University of London, London, E1 2AT, UK.
  • Puthucheary ZA; Department of Infection and Immunity, Royal London Hospital, Barts Health NHS Trust, London, E1 1FR, UK.
  • Pearse RM; Blizard Institute, Queen Mary University of London, London, E1 2AT, UK.
  • Orkin CM; Department of Infection and Immunity, Royal London Hospital, Barts Health NHS Trust, London, E1 1FR, UK.
  • Prowle JR; William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK.
Sci Rep ; 12(1): 3721, 2022 03 08.
Article in En | MEDLINE | ID: mdl-35260620
It is unclear if changes in public behaviours, developments in COVID-19 treatments, improved patient care, and directed policy initiatives have altered outcomes for minority ethnic groups in the second pandemic wave. This was a prospective analysis of patients aged ≥ 16 years having an emergency admission with SARS-CoV-2 infection between 01/09/2020 and 17/02/2021 to acute NHS hospitals in east London. Multivariable survival analysis was used to assess associations between ethnicity and mortality accounting for predefined risk factors. Age-standardised rates of hospital admission relative to the local population were compared between ethnic groups. Of 5533 patients, the ethnic distribution was White (n = 1805, 32.6%), Asian/Asian British (n = 1983, 35.8%), Black/Black British (n = 634, 11.4%), Mixed/Other (n = 433, 7.8%), and unknown (n = 678, 12.2%). Excluding 678 patients with missing data, 4855 were included in multivariable analysis. Relative to the White population, Asian and Black populations experienced 4.1 times (3.77-4.39) and 2.1 times (1.88-2.33) higher rates of age-standardised hospital admission. After adjustment for various patient risk factors including age, sex, and socioeconomic deprivation, Asian patients were at significantly higher risk of death within 30 days (HR 1.47 [1.24-1.73]). No association with increased risk of death in hospitalised patients was observed for Black or Mixed/Other ethnicity. Asian and Black ethnic groups continue to experience poor outcomes following COVID-19. Despite higher-than-expected rates of hospital admission, Black and Asian patients also experienced similar or greater risk of death in hospital since the start of the pandemic, implying a higher overall risk of COVID-19 associated death in these communities.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ethnicity / COVID-19 / Hospitalization Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Sci Rep Year: 2022 Document type: Article Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ethnicity / COVID-19 / Hospitalization Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Sci Rep Year: 2022 Document type: Article Country of publication: