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c-Maf: The magic wand that turns on LSEC fate.
Smith, Anna R; Gouon-Evans, Valerie.
Affiliation
  • Smith AR; Section of Gastroenterology, Center for Regenerative Medicine (CReM), Department of Medicine, Boston University and Boston Medical Center, Boston, MA, USA.
  • Gouon-Evans V; Section of Gastroenterology, Center for Regenerative Medicine (CReM), Department of Medicine, Boston University and Boston Medical Center, Boston, MA, USA. Electronic address: valerige@bu.edu.
Cell Stem Cell ; 29(4): 491-493, 2022 04 07.
Article in En | MEDLINE | ID: mdl-35395181
ABSTRACT
In this issue of Cell Stem Cell, Gómez-Salinero et al. (2022) identify c-Maf as a driver for murine liver sinusoidal endothelial cell (LSEC) fate and function during liver development, homeostasis, and repair. Similarly, c-Maf defines human LSECs, and its overexpression specializes generic HUVECs into functional induced-LSECs, potentiating regenerative therapeutics.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endothelial Cells / Proto-Oncogene Proteins c-maf / Liver Limits: Animals / Humans Language: En Journal: Cell Stem Cell Year: 2022 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endothelial Cells / Proto-Oncogene Proteins c-maf / Liver Limits: Animals / Humans Language: En Journal: Cell Stem Cell Year: 2022 Document type: Article Affiliation country: