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A rare genetic variant in the cleavage site of prepro-orexin is associated with idiopathic hypersomnia.
Miyagawa, Taku; Tanaka, Susumu; Shimada, Mihoko; Sakai, Noriaki; Tanida, Kotomi; Kotorii, Nozomu; Kotorii, Tatayu; Ariyoshi, Yu; Hashizume, Yuji; Ogi, Kimihiro; Hiejima, Hiroshi; Kanbayashi, Takashi; Imanishi, Aya; Ikegami, Azusa; Kamei, Yuichi; Hida, Akiko; Wada, Yamato; Miyamoto, Masayuki; Takami, Masanori; Kondo, Hideaki; Tamura, Yoshiyuki; Taniyama, Yukari; Omata, Naoto; Mizuno, Tomoyuki; Moriya, Shunpei; Furuya, Hirokazu; Kato, Mitsuhiro; Kato, Kayoko; Ishigooka, Jun; Tsuruta, Kazuhito; Chiba, Shigeru; Yamada, Naoto; Okawa, Masako; Hirata, Koichi; Kuroda, Kenji; Kume, Kazuhiko; Uchimura, Naohisa; Kitada, Masaaki; Kodama, Tohru; Inoue, Yuichi; Nishino, Seiji; Mishima, Kazuo; Tokunaga, Katsushi; Honda, Makoto.
Affiliation
  • Miyagawa T; Sleep Disorders Project, Department of Psychiatry and Behavioral Sciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan. miyagawa-tk@igakuken.or.jp.
  • Tanaka S; Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. miyagawa-tk@igakuken.or.jp.
  • Shimada M; Department of Anatomy, Faculty of Medicine, Kansai Medical University, Osaka, Japan.
  • Sakai N; Sleep Disorders Project, Department of Psychiatry and Behavioral Sciences, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
  • Tanida K; Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Kotorii N; Genome Medical Science Project (Toyama), National Center for Global Health and Medicine, Tokyo, Japan.
  • Kotorii T; Sleep and Circadian Neurobiology Laboratory, School of Medicine, Stanford University, Stanford, CA, USA.
  • Ariyoshi Y; Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Hashizume Y; Department of Neuropsychiatry, Kurume University School of Medicine, Fukuoka, Japan.
  • Ogi K; Kotorii Isahaya Hospital, Nagasaki, Japan.
  • Hiejima H; Kotorii Isahaya Hospital, Nagasaki, Japan.
  • Kanbayashi T; Ariyoshi Sleep Clinic, Fukuoka, Japan.
  • Imanishi A; Department of Neuropsychiatry, Kurume University School of Medicine, Fukuoka, Japan.
  • Ikegami A; Department of Neuropsychiatry, Kurume University School of Medicine, Fukuoka, Japan.
  • Kamei Y; Department of Neuropsychiatry, Kurume University School of Medicine, Fukuoka, Japan.
  • Hida A; International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Ibaraki, Japan.
  • Wada Y; Ibaraki Prefectural Medical Center of Psychiatry, Ibaraki, Japan.
  • Miyamoto M; Department of Neuropsychiatry, Akita University Graduate School of Medicine, Akita, Japan.
  • Takami M; Sleep Center, Kuwamizu Hospital, Kumamoto, Japan.
  • Kondo H; Department of Laboratory Medicine, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan.
  • Tamura Y; Kamisuwa Hospital, Nagano, Japan.
  • Taniyama Y; Department of Sleep-Wake Disorders, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.
  • Omata N; Department of Psychiatry, Hannan Hospital, Osaka, Japan.
  • Mizuno T; Department of Neurology, Dokkyo Medical University, Tochigi, Japan.
  • Moriya S; Department of Psychiatry, Shiga University of Medical Science, Shiga, Japan.
  • Furuya H; International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Ibaraki, Japan.
  • Kato M; Department of Psychiatry and Neurology, Asahikawa Medical University, Hokkaido, Japan.
  • Kato K; Department of Neurology, Junwakai Memorial Hospital, Miyazaki, Japan.
  • Ishigooka J; Department of Nursing, Faculty of Health Science, Fukui Health Science University, Fukui, Japan.
  • Tsuruta K; Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
  • Chiba S; Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
  • Yamada N; Department of Psychiatry, Tokyo Women's Medical University School of Medicine, Tokyo, Japan.
  • Okawa M; Department of Neurology, Neuro-Muscular Center, National Omuta Hospital, Fukuoka, Japan.
  • Hirata K; Department of Neurology, Kochi Medical School, Kochi University, Kochi, Japan.
  • Kuroda K; Department of Pediatrics, Yamagata University Faculty of Medicine, Yamagata, Japan.
  • Kume K; Department of Pediatrics, Showa University School of Medicine, Tokyo, Japan.
  • Uchimura N; Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Kitada M; Institute of CNS Pharmacology, Tokyo, Japan.
  • Kodama T; Department of Neurology, Junwakai Memorial Hospital, Miyazaki, Japan.
  • Inoue Y; Department of Psychiatry and Neurology, Asahikawa Medical University, Hokkaido, Japan.
  • Nishino S; Department of Psychiatry, Shiga University of Medical Science, Shiga, Japan.
  • Mishima K; Department of Sleep Medicine, Shiga University of Medical Science, Shiga, Japan.
  • Tokunaga K; Japan Foundation for Neuroscience and Mental Health, Tokyo, Japan.
  • Honda M; Department of Somnology, Tokyo Medical University, Tokyo, Japan.
NPJ Genom Med ; 7(1): 29, 2022 Apr 12.
Article in En | MEDLINE | ID: mdl-35414074
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Risk_factors_studies Language: En Journal: NPJ Genom Med Year: 2022 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Risk_factors_studies Language: En Journal: NPJ Genom Med Year: 2022 Document type: Article Affiliation country: Country of publication: