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Transplantation Without Overimmunosuppression (TWO) study protocol: a phase 2b randomised controlled single-centre trial of regulatory T cell therapy to facilitate immunosuppression reduction in living donor kidney transplant recipients.
Brook, Matthew Oliver; Hester, Joanna; Petchey, William; Rombach, Ines; Dutton, Susan; Bottomley, Matthew James; Black, Joanna; Abdul-Wahab, Seetha; Bushell, Andrew; Lombardi, Giovanna; Wood, Kathryn; Friend, Peter; Harden, Paul; Issa, Fadi.
Affiliation
  • Brook MO; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK matthew.brook@nds.ox.ac.uk.
  • Hester J; Oxford Transplant Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
  • Petchey W; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
  • Rombach I; Oxford Transplant Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
  • Dutton S; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Bottomley MJ; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Black J; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
  • Abdul-Wahab S; Oxford Transplant Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
  • Bushell A; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
  • Lombardi G; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
  • Wood K; NIHR Biomedical Research Centre GMP unit, Guy's Hospital, London, UK.
  • Friend P; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
  • Harden P; NIHR Biomedical Research Centre GMP unit, Guy's Hospital, London, UK.
  • Issa F; Peter Gorer Department of Immunobiology, King's College London Faculty of Life Sciences and Medicine, London, UK.
BMJ Open ; 12(4): e061864, 2022 04 15.
Article in En | MEDLINE | ID: mdl-35428650
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Kidney Transplantation / T-Lymphocytes, Regulatory Type of study: Clinical_trials / Guideline Aspects: Ethics Limits: Humans Language: En Journal: BMJ Open Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Kidney Transplantation / T-Lymphocytes, Regulatory Type of study: Clinical_trials / Guideline Aspects: Ethics Limits: Humans Language: En Journal: BMJ Open Year: 2022 Document type: Article Affiliation country: Country of publication: