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A VSV-based assay quantifies coronavirus Mpro/3CLpro/Nsp5 main protease activity and chemical inhibition.
Heilmann, Emmanuel; Costacurta, Francesco; Geley, Stephan; Mogadashi, Seyad Arad; Volland, Andre; Rupp, Bernhard; Harris, Reuben Stewart; von Laer, Dorothee.
Affiliation
  • Heilmann E; Institute of Virology, Medical University of Innsbruck, Innsbruck, Austria. emmanuel.heilmann@i-med.ac.at.
  • Costacurta F; Institute of Virology, Medical University of Innsbruck, Innsbruck, Austria.
  • Geley S; Division of Pathophysiology, Medical University of Innsbruck, Innsbruck, Austria.
  • Mogadashi SA; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, MN, 55455, USA.
  • Volland A; Institute of Virology, Medical University of Innsbruck, Innsbruck, Austria.
  • Rupp B; Institute of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria.
  • Harris RS; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, MN, 55455, USA.
  • von Laer D; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, MN, 55455, USA.
Commun Biol ; 5(1): 391, 2022 04 27.
Article in En | MEDLINE | ID: mdl-35478219
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cysteine Endopeptidases / COVID-19 Limits: Humans Language: En Journal: Commun Biol Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cysteine Endopeptidases / COVID-19 Limits: Humans Language: En Journal: Commun Biol Year: 2022 Document type: Article Affiliation country: Country of publication: