Borane promoted aryl transfer reaction for the synthesis of α-aryl functionalised ß-hydroxy and ß-keto esters.
Org Biomol Chem
; 20(21): 4298-4302, 2022 06 01.
Article
in En
| MEDLINE
| ID: mdl-35575126
ABSTRACT
The synthesis of a series of α-aryl or α-alkyl functionalised ß-hydroxy and ß-keto esters has been achieved by reacting α-diazoesters with boranes, and aldehydes, ketones, anhydrides, nitriles, esters or isocyanates. In a mild reaction protocol, 26 examples are presented in yields up to 73%.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Boranes
/
Esters
Language:
En
Journal:
Org Biomol Chem
Journal subject:
BIOQUIMICA
/
QUIMICA
Year:
2022
Document type:
Article
Affiliation country:
Publication country:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM