Impact of human placental derivative allografts on functional and oncological outcomes after radical prostatectomy: a literature review.
J Robot Surg
; 17(2): 265-273, 2023 Apr.
Article
in En
| MEDLINE
| ID: mdl-35717486
ABSTRACT
Post radical prostatectomy (RP) erectile dysfunction and incontinence impacts quality of life for patients. In an objective to hasten the recovery of these functional outcomes, human placental derived allografts laid on neurovascular bundles (NVB) have been investigated. These grafts include amniotic membranes (AM) chorionic membranes (CM) or umbilical cord (UC) allografts. A literature review performed using the MeSH terms "AMNION" OR "CHORION" OR "AMNIOTIC MEMBRANE" OR "UMBILICAL CORD" AND "PROSTATE CANCER" from no specified start date, to April 2022. 163 articles were retrieved, with 149 articles excluded. 14 articles were eligible and analysed. 5 articles were included in this review for an analysis on comparative outcomes. The average return to potency was statistically significant in the intervention groups. Positive surgical margin (PSM) rates showed a higher rate in the control groups. BCR was observed at a lower rate in the interventional group. This review reveals a benefit from human placental allograft's ability to hasten post RP functional recovery, without impacting oncological control.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Prostatic Neoplasms
/
Robotic Surgical Procedures
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Erectile Dysfunction
Type of study:
Systematic_reviews
Aspects:
Patient_preference
Limits:
Female
/
Humans
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Male
/
Pregnancy
Language:
En
Journal:
J Robot Surg
Year:
2023
Document type:
Article
Affiliation country: