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Computational fluid dynamic simulations of temperature, cryoconcentration, and stress time during large-scale freezing and thawing of monoclonal antibody solutions.
Bluemel, Oliver; Pavlisic, Andraz; Likozar, Blaz; Rodrigues, Miguel A; Geraldes, Vitor; Bechtold-Peters, Karoline; Friess, Wolfgang.
Affiliation
  • Bluemel O; Pharmaceutical Technology and Biopharmaceutics, Department of Pharmacy, Ludwig-Maximilians-Universitaet Muenchen, 81377 Munich, Germany.
  • Pavlisic A; Laboratory of Catalysis and Chemical Reaction Engineering, National Institute of Chemistry, 1000 Ljubljana, Slovenia.
  • Likozar B; Laboratory of Catalysis and Chemical Reaction Engineering, National Institute of Chemistry, 1000 Ljubljana, Slovenia.
  • Rodrigues MA; Centro de Química Estrutural, Department of Chemical Engineering, Instituto Superior Técnico, Lisboa 1049-001, Portugal.
  • Geraldes V; CeFEMA, Department of Chemical Engineering, Instituto Superior Técnico, Lisboa 1049-001, Portugal.
  • Bechtold-Peters K; Technical Research and Development, Novartis Pharma AG, 4002 Basel, Switzerland. Electronic address: wolfgang.friess@lrz.uni-muenchen.de.
  • Friess W; Pharmaceutical Technology and Biopharmaceutics, Department of Pharmacy, Ludwig-Maximilians-Universitaet Muenchen, 81377 Munich, Germany.
Eur J Pharm Biopharm ; 177: 107-112, 2022 Aug.
Article in En | MEDLINE | ID: mdl-35764219
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biodiversity / Antibodies, Monoclonal Type of study: Prognostic_studies Language: En Journal: Eur J Pharm Biopharm Journal subject: FARMACIA / FARMACOLOGIA Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biodiversity / Antibodies, Monoclonal Type of study: Prognostic_studies Language: En Journal: Eur J Pharm Biopharm Journal subject: FARMACIA / FARMACOLOGIA Year: 2022 Document type: Article Affiliation country: Country of publication: