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Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion.
Giroux, Nicholas S; Ding, Shengli; McClain, Micah T; Burke, Thomas W; Petzold, Elizabeth; Chung, Hong A; Rivera, Grecia O; Wang, Ergang; Xi, Rui; Bose, Shree; Rotstein, Tomer; Nicholson, Bradly P; Chen, Tianyi; Henao, Ricardo; Sempowski, Gregory D; Denny, Thomas N; De Ussel, Maria Iglesias; Satterwhite, Lisa L; Ko, Emily R; Ginsburg, Geoffrey S; Kraft, Bryan D; Tsalik, Ephraim L; Shen, Xiling; Woods, Christopher W.
Affiliation
  • Giroux NS; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, 27708, USA.
  • Ding S; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, 27708, USA.
  • McClain MT; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, NC, 27710, USA.
  • Burke TW; Durham Veterans Affairs Health Care System, Durham, NC, 27705, USA.
  • Petzold E; Division of Infectious Diseases, School of Medicine, Duke University Medical Center, 40 Duke Medicine Circle, Durham, NC, 27710-4000, USA.
  • Chung HA; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, NC, 27710, USA.
  • Rivera GO; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, NC, 27710, USA.
  • Wang E; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, 27708, USA.
  • Xi R; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, 27708, USA.
  • Bose S; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, 27708, USA.
  • Rotstein T; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, 27708, USA.
  • Nicholson BP; Department of Pharmacology and Cancer Biology, School of Medicine, Duke University, Durham, NC, 27710, USA.
  • Chen T; Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, 27708, USA.
  • Henao R; Institute for Medical Research, Durham, NC, 27705, USA.
  • Sempowski GD; Department of Molecular Genetics and Microbiology, School of Medicine, Duke University, Durham, NC, 27710, USA.
  • Denny TN; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, NC, 27710, USA.
  • De Ussel MI; Duke Human Vaccine Institute and Department of Medicine, School of Medicine, Duke University, Durham, NC, 27710, USA.
  • Satterwhite LL; Duke Human Vaccine Institute and Department of Medicine, School of Medicine, Duke University, Durham, NC, 27710, USA.
  • Ko ER; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, NC, 27710, USA.
  • Ginsburg GS; Department of Civil and Environmental Engineering, Pratt School of Engineering, Duke University, Durham, NC, 27708, USA.
  • Kraft BD; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, NC, 27710, USA.
  • Tsalik EL; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, NC, 27710, USA.
  • Shen X; Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, NC, 27710, USA.
  • Woods CW; Durham Veterans Affairs Health Care System, Durham, NC, 27705, USA.
Sci Rep ; 12(1): 11714, 2022 07 09.
Article in En | MEDLINE | ID: mdl-35810186
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatin / COVID-19 Limits: Humans Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatin / COVID-19 Limits: Humans Language: En Journal: Sci Rep Year: 2022 Document type: Article Affiliation country: Country of publication: