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Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity.
Hartwell, Brittany L; Melo, Mariane B; Xiao, Peng; Lemnios, Ashley A; Li, Na; Chang, Jason Y H; Yu, Jingyou; Gebre, Makda S; Chang, Aiquan; Maiorino, Laura; Carter, Crystal; Moyer, Tyson J; Dalvie, Neil C; Rodriguez-Aponte, Sergio A; Rodrigues, Kristen A; Silva, Murillo; Suh, Heikyung; Adams, Josetta; Fontenot, Jane; Love, J Christopher; Barouch, Dan H; Villinger, Francois; Ruprecht, Ruth M; Irvine, Darrell J.
Affiliation
  • Hartwell BL; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Melo MB; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.
  • Xiao P; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Lemnios AA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.
  • Li N; Consortium for HIV/AIDS Vaccine Development (CHAVD), Scripps Research Institute, La Jolla, CA 92037, USA.
  • Chang JYH; New Iberia Research Center, University of Louisiana at Lafayette, New Iberia, LA 70560, USA.
  • Yu J; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Gebre MS; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Chang A; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Maiorino L; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.
  • Carter C; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.
  • Moyer TJ; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.
  • Dalvie NC; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.
  • Rodriguez-Aponte SA; Harvard Medical School, Boston, MA 02115, USA.
  • Rodrigues KA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Silva M; New Iberia Research Center, University of Louisiana at Lafayette, New Iberia, LA 70560, USA.
  • Suh H; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Adams J; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.
  • Fontenot J; Consortium for HIV/AIDS Vaccine Development (CHAVD), Scripps Research Institute, La Jolla, CA 92037, USA.
  • Love JC; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Barouch DH; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Villinger F; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Ruprecht RM; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Irvine DJ; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Sci Transl Med ; 14(654): eabn1413, 2022 07 20.
Article in En | MEDLINE | ID: mdl-35857825
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / COVID-19 Limits: Animals Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / COVID-19 Limits: Animals Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2022 Document type: Article Affiliation country: Country of publication: