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Progranulin-derived granulin E and lysosome membrane protein CD68 interact to reciprocally regulate their protein homeostasis.
Santos, Mariela Nunez; Paushter, Daniel H; Zhang, Tingting; Wu, Xiaochun; Feng, Tuancheng; Lou, Jiaoying; Du, Huan; Becker, Stephanie M; Fragoza, Robert; Yu, Haiyuan; Hu, Fenghua.
Affiliation
  • Santos MN; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, USA.
  • Paushter DH; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, USA.
  • Zhang T; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, USA.
  • Wu X; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, USA.
  • Feng T; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, USA.
  • Lou J; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, USA; Department of Gynecology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, P. R. China.
  • Du H; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, USA.
  • Becker SM; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, USA.
  • Fragoza R; Department of Computational Biology, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, USA.
  • Yu H; Department of Computational Biology, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, USA.
  • Hu F; Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, USA. Electronic address: fh87@cornell.edu.
J Biol Chem ; 298(9): 102348, 2022 09.
Article in En | MEDLINE | ID: mdl-35933009
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antigens, Differentiation, Myelomonocytic / Antigens, CD / Lysosomal Membrane Proteins / Proteostasis / Granulins Type of study: Prognostic_studies Language: En Journal: J Biol Chem Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antigens, Differentiation, Myelomonocytic / Antigens, CD / Lysosomal Membrane Proteins / Proteostasis / Granulins Type of study: Prognostic_studies Language: En Journal: J Biol Chem Year: 2022 Document type: Article Affiliation country: Country of publication: