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A possible covalent xanthine oxidase inhibitor TS10: Inhibition mechanism, metabolites identification and PDPK assessment.
Zhang, Ting-Jian; Zhang, Xu; Xu, En-Yu; Wang, Zhao-Ran; Zhang, Zhen-Hao; Wang, Qiu-Yin; Wang, Lin; Wen, Yan-Qing; Meng, Fan-Hao.
Affiliation
  • Zhang TJ; School of Pharmacy, China Medical University, 77 Puhe Road, North New Area, Shenyang 110122, China.
  • Zhang X; School of Pharmacy, China Medical University, 77 Puhe Road, North New Area, Shenyang 110122, China.
  • Xu EY; School of Forensic Medicine, China Medical University, Shenyang 110122, China.
  • Wang ZR; School of Pharmacy, China Medical University, 77 Puhe Road, North New Area, Shenyang 110122, China.
  • Zhang ZH; School of Pharmacy, China Medical University, 77 Puhe Road, North New Area, Shenyang 110122, China.
  • Wang QY; School of Pharmacy, China Medical University, 77 Puhe Road, North New Area, Shenyang 110122, China.
  • Wang L; School of Pharmacy, China Medical University, 77 Puhe Road, North New Area, Shenyang 110122, China.
  • Wen YQ; School of Pharmacy, China Medical University, 77 Puhe Road, North New Area, Shenyang 110122, China; Department of Pharmacy, The Fourth Affiliated Hospital of China Medical University, Shenyang, China. Electronic address: 1428728526@qq.com.
  • Meng FH; School of Pharmacy, China Medical University, 77 Puhe Road, North New Area, Shenyang 110122, China. Electronic address: fhmeng@cmu.edu.cn.
Bioorg Chem ; 128: 106064, 2022 11.
Article in En | MEDLINE | ID: mdl-35987190
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uric Acid / Xanthine Oxidase Type of study: Diagnostic_studies Language: En Journal: Bioorg Chem Year: 2022 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uric Acid / Xanthine Oxidase Type of study: Diagnostic_studies Language: En Journal: Bioorg Chem Year: 2022 Document type: Article Affiliation country: Country of publication: