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Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies.
Lutz, Emi A; Agarwal, Yash; Momin, Noor; Cowles, Sarah C; Palmeri, Joseph R; Duong, Ellen; Hornet, Vladlena; Sheen, Allison; Lax, Brianna M; Rothschilds, Adrienne M; Irvine, Darrell J; Spranger, Stefani; Wittrup, K Dane.
Affiliation
  • Lutz EA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Agarwal Y; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Momin N; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Cowles SC; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Palmeri JR; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Duong E; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Hornet V; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Sheen A; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Lax BM; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Rothschilds AM; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Irvine DJ; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Spranger S; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Wittrup KD; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139.
Proc Natl Acad Sci U S A ; 119(36): e2205983119, 2022 09 06.
Article in En | MEDLINE | ID: mdl-36037341
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon Type I / Aluminum Hydroxide / Immunotherapy Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon Type I / Aluminum Hydroxide / Immunotherapy Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Document type: Article Country of publication: