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Statistical shape representation of the thoracic aorta: accounting for major branches of the aortic arch.
Wiputra, Hadi; Matsumoto, Shion; Wagenseil, Jessica E; Braverman, Alan C; Voeller, Rochus K; Barocas, Victor H.
Affiliation
  • Wiputra H; Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA.
  • Matsumoto S; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
  • Wagenseil JE; Department of Mechanical Engineering & Materials Science, Washington University, St. Louis, MO, USA.
  • Braverman AC; Department of Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA.
  • Voeller RK; Department of Surgery, University of Minnesota, Minneapolis, MN, USA.
  • Barocas VH; Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA.
Comput Methods Biomech Biomed Engin ; 26(13): 1557-1571, 2023 Oct.
Article in En | MEDLINE | ID: mdl-36165506
ABSTRACT
Statistical shape modeling (SSM) is an emerging tool for risk assessment of thoracic aortic aneurysm. However, the head branches of the aortic arch are often excluded in SSM. We introduced an SSM strategy based on principal component analysis that accounts for aortic branches and applied it to a set of patient scans. Computational fluid dynamics were performed on the reconstructed geometries to identify the extent to which branch model accuracy affects the calculated wall shear stress (WSS) and pressure. Surface-averaged and location-specific values of pressure did not change significantly, but local WSS error was high near branches when inaccurately modeled.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aorta, Thoracic / Aortic Aneurysm, Thoracic Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Comput Methods Biomech Biomed Engin Journal subject: ENGENHARIA BIOMEDICA / FISIOLOGIA Year: 2023 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aorta, Thoracic / Aortic Aneurysm, Thoracic Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Comput Methods Biomech Biomed Engin Journal subject: ENGENHARIA BIOMEDICA / FISIOLOGIA Year: 2023 Document type: Article Affiliation country: