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Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis.
Hindy, George; Tyrrell, Daniel J; Vasbinder, Alexi; Wei, Changli; Presswalla, Feriel; Wang, Hui; Blakely, Pennelope; Ozel, Ayse Bilge; Graham, Sarah; Holton, Grace H; Dowsett, Joseph; Fahed, Akl C; Amadi, Kingsley-Michael; Erne, Grace K; Tekmulla, Annika; Ismail, Anis; Launius, Christopher; Sotoodehnia, Nona; Pankow, James S; Thørner, Lise Wegner; Erikstrup, Christian; Pedersen, Ole Birger; Banasik, Karina; Brunak, Søren; Ullum, Henrik; Eugen-Olsen, Jesper; Ostrowski, Sisse Rye; Haas, Mary E; Nielsen, Jonas B; Lotta, Luca A; Engström, Gunnar; Melander, Olle; Orho-Melander, Marju; Zhao, Lili; Murthy, Venkatesh L; Pinsky, David J; Willer, Cristen J; Heckbert, Susan R; Reiser, Jochen; Goldstein, Daniel R; Desch, Karl C; Hayek, Salim S.
Affiliation
  • Hindy G; Department of Clinical Sciences, Lund University, Malmö, Sweden.
  • Tyrrell DJ; Department of Population Medicine, Qatar University College of Medicine, QU Health, Doha, Qatar.
  • Vasbinder A; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Wei C; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Presswalla F; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Wang H; Department of Medicine, Rush University Medical Center, Chicago, Illinois, USA.
  • Blakely P; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Ozel AB; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Graham S; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Holton GH; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA.
  • Dowsett J; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA.
  • Fahed AC; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Amadi KM; Department of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark.
  • Erne GK; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Tekmulla A; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Ismail A; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Launius C; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Sotoodehnia N; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Pankow JS; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Thørner LW; Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, Washington, USA.
  • Erikstrup C; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA.
  • Pedersen OB; Department of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark.
  • Banasik K; Department of Immunology, Aarhus University Hospital, Aarhus, Denmark.
  • Brunak S; Department of Immunology, Zealand University Hospital, Køge, Denmark.
  • Ullum H; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Eugen-Olsen J; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Ostrowski SR; State Serum Institute, Copenhagen, Denmark.
  • Haas ME; Department of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark.
  • Lotta LA; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA.
  • Engström G; Regeneron Genetics Center, Regeneron Pharmaceuticals Inc., Tarrytown, New York, USA.
  • Orho-Melander M; Department of Clinical Sciences, Lund University, Malmö, Sweden.
  • Zhao L; Department of Clinical Sciences, Lund University, Malmö, Sweden.
  • Murthy VL; Department of Clinical Sciences, Lund University, Malmö, Sweden.
  • Pinsky DJ; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
  • Willer CJ; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Heckbert SR; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Reiser J; Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Goldstein DR; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA.
  • Desch KC; Department of Epidemiology, University of Washington, Seattle, Washington, USA.
  • Hayek SS; Department of Medicine, Rush University Medical Center, Chicago, Illinois, USA.
J Clin Invest ; 132(24)2022 12 15.
Article in En | MEDLINE | ID: mdl-36194491
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Atherosclerosis / Receptors, Urokinase Plasminogen Activator Type of study: Clinical_trials / Prognostic_studies / Systematic_reviews Limits: Animals / Humans Language: En Journal: J Clin Invest Year: 2022 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Atherosclerosis / Receptors, Urokinase Plasminogen Activator Type of study: Clinical_trials / Prognostic_studies / Systematic_reviews Limits: Animals / Humans Language: En Journal: J Clin Invest Year: 2022 Document type: Article Affiliation country: Country of publication: